Browsing by Author "Mahidol University. Office of Veterinary Medical Care, National Laboratory Animal Center"

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    การศึกษาความดันโลหิตในหนูแรทสายพันธุ์ความดันโลหิตสูงของศูนย์สัตว์ทดลองแห่งชาติ
    (2012) สุรชัย จันทร์ทิพย์; อภิสิทธิ เหล่าสันติสุข; พรรัตนา ช่อมณี; วสันต์ แก้วมณี; สุเมธ อาภาวงษ์; คิน หม่อง ซอ; กาญจนา เข่งคุ้ม; Surachai Chantip; Apisit laosantisuk; Pornrattana Chomanee; Wasan Keawmanee; Sumate Ampawong; Zaw, Khin Maung; Kanchana Kaengkhum; Mahidol University. Office of Academic Services, National Laboratory Animal Center; Mahidol University. Office of Veterinary Medical Care, National Laboratory Animal Center
    Spontaneous hypertensive rat (SHR) is a genetic model of hypertension rat that is wildly accepted in biomedical research because its characteristic might be shared with idiopathic hypertension in human. National Laboratory Animal Center, Mahidol University has been breeding and selecting this strain (as subline namely SHR/KyoMlac) that kindly donated by Kyoto University, Japan. This study was conducted to evaluate the blood pressure (systolic and diastolic) and growth rate between SHR/KyoMlac (hypertensive) and WMN/NrsMlac (normotensive). The results showed that systolic blood pressure of adult hypertensive rat (130-150 mmHg) was significantly higher than adult normotensive rat (90-120 mmHg.) Contrast to growth rate of hypertensive rat was significantly lower than normotensive rat.