Browsing by Author "Mogens Jensenius"

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    Rabies post-exposure prophylaxis started during or after travel: A GeoSentinel analysis
    (2018-11-01) Philippe Gautret; Kristina M. Angelo; Hilmir Asgeirsson; David G. Lalloo; Marc Shaw; Eli Schwartz; Michael Libman; Kevin C. Kain; Watcharapong Piyaphanee; Holly Murphy; Karin Leder; Jean Vincelette; Mogens Jensenius; Jesse Waggoner; Daniel Leung; Sarah Borwein; Lucille Blumberg; Patricia Schlagenhauf; Elizabeth D. Barnett; Davidson H. Hamer; Oslo University Hospital; Aix Marseille Université; National Institute for Communicable Diseases; University of Utah, School of Medicine; Centers for Disease Control and Prevention; Liverpool School of Tropical Medicine; James Cook University, Australia; Monash University; Karolinska University Hospital; Boston University School of Public Health; University of Toronto; Mahidol University; University of Zurich; Centre Hospitalier de L'Universite de Montreal; Boston University School of Medicine; Tel Aviv University, Sackler Faculty of Medicine; McGill University; Emory University School of Medicine; CIWEC Travel Medicine Centre; Central Health Medical Practice; Worldwise Travellers Health Centres of New Zealand
    © 2018, Public Library of Science. All rights reserved. https://creativecommons.org/publicdomain/zero/1.0/. Background: Recent studies demonstrate that rabies post-exposure prophylaxis (RPEP) in international travelers is suboptimal, with only 5–20% of travelers receiving rabies immune globulin (RIG) in the country of exposure when indicated. We hypothesized that travelers may not be receiving RIG appropriately, and practices may vary between countries. We aim to describe the characteristics of travelers who received RIG and/or RPEP during travel. Methodology/Principal findings: We conducted a multi-center review of international travelers exposed to potentially rabid animals, collecting information on RPEP administration. Travelers who started RPEP before (Group A) and at (Group B) presentation to a GeoSentinel clinic during September 2014–July 2017 were included. We included 920 travelers who started RPEP. About two-thirds of Group A travelers with an indication for rabies immunoglobulin (RIG) did not receive it. Travelers exposed in Indonesia were less likely to receive RIG in the country of exposure (relative risk: 0.30; 95% confidence interval: 0.12–0.73; P = 0.01). Travelers exposed in Thailand [Relative risk (RR) 1.38, 95% Confidence Interval (95% CI): 1.0–1.8; P = 0.02], Sri Lanka (RR 3.99, 95% CI: 3.99–11.9; P = 0.013), and the Philippines (RR 19.95, 95% CI: 2.5–157.2; P = 0.01), were more likely to receive RIG in the country of exposure. Conclusions/Significance: This analysis highlights gaps in early delivery of RIG to travelers and identifies specific countries where travelers may be more or less likely to receive RIG. More detailed country-level information helps inform risk education of international travelers regarding appropriate rabies prevention.
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    Regional variation in travel-related illness acquired in Africa, March 1997-May 2011
    (2014-01-01) Marc Mendelson; Pauline V. Han; Peter Vincent; Frank von Sonnenburg; Jakob P. Cramer; Louis Loutan; Kevin C. Kain; Philippe Parola; Stefan Hagmann; Effrossyni Gkrania-Klotsas; Mark Sotir; Patricia Schlagenhauf; Rahul Anand; Hilmir Ásgeirsson; Elizabeth D. Barnett; Sarah Borwein; Gerd Dieter Burchard; John D. Cahill; Daniel Campion; Francesco Castelli; Eric Caumes; Lin H. Chen; Bradley A. Connor; Christina M. Coyle; Jakob Cramer; Jane Eason; Cécile Ficko; Vanessa Field; David O. Freedman; Abram Goorhuis; Martin P. Grobusch; Alejandra Gurtman; Devon C. Hale; Annemarie Hern; Noreen Hynes; Mogens Jensenius; Robert Kass; Amy D. Klion; Phyllis E. Kozarsky; Karin Leder; Carmelo Licitra; Rogelio López-Vélez; Michael W. Lynch; Alberto Matteelli; Anne McCarthy; George MckInley; Susan McLellan; José Antonio Pérez Molina; Robert Muller; Thomas B. Nutman; Alice Pérignon; Phi Truong Hoang Phu; Watcharapong Piyaphanee; Christophe Rapp; David Roesel; Eli Schwartz; Marc Shaw; Udomsak Silachamroon; William Stauffer; Natsuo Tachikawa; Joseph Torresi; Johan Ursing; Jean Vincelette; Patricia Walker; Andy Wang; Mary E. Wilson; Henry Wu; Yukihiro Yoshimura; University of Cape Town; Centers for Disease Control and Prevention; Tokai Medicross Travel Clinic; Ludwig-Maximilians-Universitat Munchen; Universitatsklinikum Hamburg-Eppendorf und Medizinische Fakultat; Universite de Geneve; University of Toronto; North University Hospital; Bronx-Lebanon Hospital Center; Cambridge University Hospitals NHS Foundation Trust; University of Zurich; University of Utah; Karolinska University Hospital; Boston University; Travel-Safe Medical Centre; Bernhard Nocht Institut fur Tropenmedizin Hamburg; St. Luke's-Roosevelt Hospital Center; InterHealth; Università degli Studi di Brescia; Hopital Universitaire Pitie Salpetriere; Harvard University; Cornell University; Albert Einstein College of Medicine of Yeshiva University; Beijing United Family Hospital and Clinics; Hopital d'Instruction des Armees Begin; University of Alabama at Birmingham; University of Amsterdam; The Mount Sinai Medical Center; Worldwise Travellers Health and Vaccination Centre; Johns Hopkins University; Oslo University Hospital; Travellers Medical and Vaccination Centre; National Institutes of Health, Bethesda; Emory University; Royal Melbourne Hospital; Orlando Regional Health Center; Hospital Ramon y Cajal; Fresno International Travel Medical Center; University of Ottawa, Canada; Tulane University; Travel Clinic Services; Hôpital Pitié-Salpêtrière; International SOS Vietnam; Mahidol University; University of Washington, Seattle; Chaim Sheba Medical Center Israel; Regions Hospital; Yokohama Municipal Citizen's Hospital; Centre Hospitalier de L'Universite de Montreal; HealthPartners
    To understand geographic variation in travel-related illness acquired in distinct African regions, we used the GeoSentinel Surveillance Network database to analyze records for 16,893 ill travelers returning from Africa over a 14-year period. Travelers to northern Africa most commonly reported gastrointestinal illnesses and dog bites. Febrile illnesses were more common in travelers returning from sub-Saharan countries. Eleven travelers died, 9 of malaria; these deaths occurred mainly among male business travelers to sub-Saharan Africa. The profile of illness varied substantially by region: malaria predominated in travelers returning from Central and Western Africa; schistosomiasis, strongyloidiasis, and dengue from Eastern and Western Africa; and loaisis from Central Africa. There were few reports of vaccine-preventable infections, HIV infection, and tuberculosis. Geographic profiling of illness acquired during travel to Africa guides targeted pretravel advice, expedites diagnosis in ill returning travelers, and may influence destination choices in tourism.