Browsing by Author "Taworntawat C."

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    Navigating Intercultural Communication Challenges: Addressing Language Barriers and Foreign Language Anxiety Among Thai Low-Cost Airline Ground Staff
    (2024-01-01) Perrodin D.D.; Liangruenrom N.; Taworntawat C.; Perrodin D.D.; Mahidol University
    This study explores the critical role of effective English communication for low-cost airlines in countries such as Thailand, which relies heavily on tourism and where English proficiency among the local population is limited. Specifically, this study focuses on intercultural communication challenges Thai ground staff face due to their restricted English ability, language-related anxiety, and perceived language barriers. The study uncovers the impact of foreign language anxiety on communication barriers with international passengers through 15 focus group discussions involving 128 ground staff from a premium low-cost Thai airline. The analysis identifies specific challenges stemming from foreign language anxiety, including difficulties in English pronunciation, unclear information delivery, and increased effort required to comprehend international passengers. The study proposes potential solutions to address these obstacles, such as incorporating mindfulness techniques into corporate training sessions for English language proficiency. This unique approach aims to help Thai ground staff overcome language barriers, facilitate effective communication, and improve customer service with international passengers by instilling a positive mindset and behavior towards English. Furthermore, the study emphasizes the importance of addressing these challenges for operational efficiency, passenger safety, and resource optimization in international air travel, where English is the primary language. Implementing these solutions can enhance intercultural communication and provide a more inclusive and satisfactory travel experience for all parties involved.
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    UHPLC-QTOF-MS Profiling of Chemical Constituents in POW9TM Cocktail with Antioxidant and Anti-Proliferative Potentials Against Vero, MCF-7 and MDA-MB-231 Cells
    (2026-02-01) Taworntawat C.; Tonkittirattanakul P.; Koonyosying P.; Perrodin D.D.; Srichairatanakool S.; Tipsuwan W.; Taworntawat C.; Mahidol University
    Breast cancer remains one of the most prevalent and lethal malignancies affecting women worldwide, underscoring the need for safer and more effective therapeutic strategies. This study investigated the phytochemical composition, antioxidant activity, and antiproliferative potential of POW9™, a proprietary botanical blend formulated from nine medicinal plant extracts. Comprehensive phytochemical profiling was performed using ultrahigh-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UHPLC-ESI-QTOF-MS) in both positive and negative ionization modes. A total of 34 compounds were identified in negative mode and 27 compounds in positive mode, comprising flavonoids, terpenoids, steroids, organic acids, peptides, glycosides, and lipids. POW9™ exhibited high total phenolic content (190.3 ± 3.5 mg gallic acid equivalents/g) and total flavonoid content (115.2 ± 1.5 mg quercetin equivalents/g), along with strong antioxidant activity, demonstrated by a 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging with a half-maximal inhibitory concentration (IC50) of 1.66 mg/mL (33.73 mg Trolox equivalents/g). Cytotoxicity assessment revealed minimal toxicity toward normal Vero cells. In contrast, POW9™ significantly inhibited the proliferation of human breast cancer cell lines in a concentration- and time-dependent manner. The IC50 values were 6.75 mg/mL for MCF-7 cells and 18.08 mg/mL for MDA-MB-231 cells after 72 h of treatment, while prolonged exposure (96 h) further enhanced antiproliferative efficacy, reducing the IC50 to 2.34 mg/mL. These findings demonstrate that POW9™ is a chemically diverse herbal formulation with potent antioxidant and selective anti-breast cancer activities, supporting its potential development as a complementary therapeutic or nutraceutical agent for breast cancer management.