Browsing by Author "Walailuk University International College of Dentistry"

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    Histopathological features assessment of suspected pathologic pericoronal tissue of embbeded teeth
    (2020-01-01) Tsheltrim Namgyel; Teeranut Chaiyasamut; Suphachai Suphangul; Natthamet Wongsirichat; Mahidol University; Walailuk University International College of Dentistry
    © 2020 Objective: This study aims to evaluate the incidence of the histopathological status of suspected pathologic pericoronal tissues of asymptomatic embedded teeth. Materials & methods: A total number of 298 specimens from 274 patients without any significant symptomatic signs and symptoms were collected. Radiological and histopathological examinations were done for the participants and the results were recorded. Sizes of the dental follicles in the radiograph were reassessed and grouped as less than 2.5 mm and 2.5 mm and above. The widest region of dental follicular space was measured by tracing the tooth contours and pericoronal space on tracing paper with caliper scale. Findings of histological diagnosis were analyzed for associations with sex, age and size of the dental follicle. Results: Biopsy results of follicular tissues showed pathological lesions such as dentigerous cyst, odontogenic keratocyst, chronic nonspecific inflammatory tissue and ameloblastoma. 48 % showed histologic changes suggestive of normal follicle and 52 % were suggestive of pathological entities. Most pathologies were encountered in the third decade and there was an increase incidence of pathological entities as the age of the patient increased at a statistical significance level of 0.01 (P = .001). There was the male predominance of incidence of pathological changes but there was no statistical significance between the follicle size group and the histologic results of the dental follicles. Conclusion: This study showed that the incidence of the histopathological status of suspected pathologic pericoronal tissues of asymptomatic embedded teeth increased following the increase age. Therefore, the suggestion of asymptomatic embedded tooth should be removal consideration.
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    Hybrid central odontogenic fibroma with central giant cell granuloma like lesion ; A case report and review of the literature
    (2019-01-01) Sakanus Vijintanawan; K. C. Kumar; Anchisa Aittiwarapoj; Natthamet Wongsirichat; Mahidol University; Walailuk University International College of Dentistry
    © 2019, Siriraj Medical Journal. The combination of central odontogenic fibroma and central giant cell granuloma is extremely rare and has been reported in only 46 cases worldwide in previous articles. The lesion is called a hybrid central odontogenic fibroma with central giant cell granuloma like lesion (HCOF-CGCG) due to a histopathological characteristics of multinucleated giant cell and odontogenic epithelium in fibro-cellular background. We report a case of HCOFCGCG in a 27-year old Thai male patient who was identified as the first case in Thailand. Radiographic examination showed a well-defined radiolucency lesion at posterior mandibular area. Enucleation and curettage were done and microscopic study revealed a fibro-cellular proliferating tissue containing numerous strands, cord of odontogenic epithelium, and numerous multinucleated giant cells. This report also included a literature review of the previous 45 cases.