Publication: Biomagnetic of Apatite-Coated Cobalt Ferrite: A Core–Shell Particle for Protein Adsorption and pH-Controlled Release.
Issued Date
2011
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eng
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Mahidol University
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Springer Link online
Bibliographic Citation
Nanoscale Research Letters. Vol.6, No.1 (2011), 1-10
Suggested Citation
I-Ming Tang, Nateetip Krishnamra, Narattaphol Charoenphandhu, Rassmidara Hoonsawat, Pon-On, W. Biomagnetic of Apatite-Coated Cobalt Ferrite: A Core–Shell Particle for Protein Adsorption and pH-Controlled Release.. Nanoscale Research Letters. Vol.6, No.1 (2011), 1-10. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10970
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Title
Biomagnetic of Apatite-Coated Cobalt Ferrite: A Core–Shell Particle for Protein Adsorption and pH-Controlled Release.
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Abstract
Magnetic nanoparticle composite with a cobalt ferrite (CoFe 2O 4, (CF)) core and an apatite (Ap) coating was synthesized using a biomineralization process in which a modified simulated body fluid (1.5SBF) solution is the source of the calcium phosphate for the apatite formation. The core-shell structure formed after the citric acid-stabilized cobalt ferrite (CFCA) particles were incubated in
the 1.5 SBF solution for 1 week. The mean particle size of CFCA-Ap is about 750 nm. A saturation magnetization of 15.56 emug -1 and a coercivity of 1808.5 Oe were observed for the CFCA-Ap obtained. Bovine serum albumin (BSA)was used as the model protein to study the adsorption and release of the proteins
by the CFCA-Ap particles. The protein adsorption by the CFCA-Ap particles followed a more typical Freundlich than Langmuir adsorption isotherm. The BSA release as a function of time became less rapid as the CFCA-Ap particles were immersed in higher pH solution, thus indicating that the BSA release is dependent on the local pH.