Publication: Cost of rotavirus diarrhea for programmatic evaluation of vaccination in Vietnam
Issued Date
2016
Resource Type
Language
eng
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Mahidol University
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BioMed Central
Bibliographic Citation
BMC Public Health. vol. 16, (2016), 777
Suggested Citation
Arthorn Riewpaiboon, Sunheang Shin, Thi Phuong Mai Le, Dinh Thiem Vu, Thi Hien Anh Nguyen, Neal Alexander, Duc Anh Dang, Rotavirus Economic Study Group Cost of rotavirus diarrhea for programmatic evaluation of vaccination in Vietnam. BMC Public Health. vol. 16, (2016), 777. doi:10.1186/s12889-016-3458-2 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/2842
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Thesis
Title
Cost of rotavirus diarrhea for programmatic evaluation of vaccination in Vietnam
Other Contributor(s)
Abstract
Background: Rotavirus is the most common etiology of diarrhea-associated hospitalizations and clinic visits in
Vietnamese children < 5 years old. To estimate the economic burden of rotavirus-associated formal healthcare
encounters, an economic study was conducted.
Methods: A cost-of-illness study was performed from a societal perspective. Data were collected from children
below the age of five years who presented to a clinic or hospital with symptoms of acute gastroenteritis (AGE).
Patient-specific information on resource use and cost was obtained through caregiver interviews and medical
chart review. Costs are presented in 2014 US dollar ($).
Results: A total of 557 children with symptoms of AGE were enrolled from March through June 2009, with mean
age of 16.5 months. Of the 340 outpatients and 217 admitted patients enrolled, 41 % tested rotavirus positive. It
was found that, from a societal perspective, the mean total cost of AGE was $175. Costs of patients with and
without rotavirus were $217 and $158, respectively. From multiple regression analysis, it was found that rotavirus
infection, patient age and receiving oral rehydration solution before visiting health facility had significant effect
on the costs.
Conclusions: This study clearly demonstrated substantial economic burden of AGE including rotavirus disease.
They were significantly greater than the previously reported cost estimates in Vietnam. These updated costs of
illness result in more favorable vaccine cost-effectiveness than in previous economic evaluations.