Publication: Measurement properties of the EQ-5D-5L compared to EQ-5D-3L in the Thai diabetes patients
Issued Date
2015
Resource Type
Language
eng
Rights
Mahidol University
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BioMed Central
Bibliographic Citation
Health and Quality of Life Outcomes. Vol.13, (2015), 14
Suggested Citation
Juntana Pattanaphesaj, Montarat Thavorncharoensap Measurement properties of the EQ-5D-5L compared to EQ-5D-3L in the Thai diabetes patients. Health and Quality of Life Outcomes. Vol.13, (2015), 14. doi:10.1186/s12955-014-0203-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/3197
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Title
Measurement properties of the EQ-5D-5L compared to EQ-5D-3L in the Thai diabetes patients
Abstract
Background: The EQ-5D is a health-related quality of life instrument which provides a simple descriptive health
profile and a single index value for health status. The latest version, the EQ-5D-5L, has been translated into more
than one hundred languages worldwide - including Thai. This study aims to assess the measurement properties of
the Thai version of the EQ-5D-5L (the 5L) compared to the EQ-5D-3L (the 3L).
Methods: A total of 117 diabetes patients treated with insulin completed a questionnaire including the 3L and the
5L. The 3L and 5L were compared in terms of distribution, ceiling, convergent validity, discriminative power,
test-retest reliability, feasibility, and patient preference. Convergent validity was tested by assessing the relationship
between each dimension of the EQ-5D and SF-36v2 using Spearman’s rank-order correlation. Discriminative power
was determined by the Shannon index (H ′) and Shannon’s Evenness index (J ′). The test-retest reliability was
assessed by examining the intraclass correlation coefficient (ICC) and Cohen’s weighted kappa coefficient.
Results: No inconsistent response was found. The 5L trended towards a slightly lower ceiling compared with the
3L (33% versus 29%). Regarding redistribution, 69% to 100% of the patients answering level 2 with the 3L version
redistributed their responses to level 2 with the 5L version while about 9% to 22% redistributed their responses to
level 3 with the 5L version. The Shannon index (H ′) improved with the 5L while the Shannon's Evenness index (J ′)
reduced slightly. Convergent validity and test-retest reliability was confirmed for both 3L and 5L.
Conclusions: Evidence supported the convergent validity and test-retest reliability of both the 3L and 5L in
diabetes patients. However, the 5L is more promising compared to the 3L in terms of a lower ceiling, more
discriminatory power, and higher preference by the respondents. Thus, the 5L should be recommended as a
preferred health-related quality of life measure in Thailand.