Publication: The importance of epigenetics in embryonic development and reproductive biotechnology
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Issued Date
2012
Resource Type
Language
eng
ISSN
1906-2257
Rights
Mahidol University
Rights Holder(s)
Faculty of Veterinary Science Mahidol University
Bibliographic Citation
Journal of Applied Animal Science. Vol.5, No.2 (May-Aug 2012), 9-26
Suggested Citation
Tuempong Wongtawan The importance of epigenetics in embryonic development and reproductive biotechnology. Journal of Applied Animal Science. Vol.5, No.2 (May-Aug 2012), 9-26. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/1691
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
The importance of epigenetics in embryonic development and reproductive biotechnology
Alternative Title(s)
ความสำคัญของสภาวะเหนือพันธุกรรม (Epigenetics) ในการเจริญเติบโตของตัวอ่อน และเทคโนโลยีทางการสืบพันธุ์
Author(s)
Abstract
It is well established that epigenetics and chromatin modifications are primary factors that can govern gene activity and nuclear architecture. They are also proven to be essential for normal embryonic development and cell differentiation. One important step during mouse development is the establishment of epigenetic reprogramming which is believed to be vital for normal growth and development, however; the mechanism is still poorly understood. Creating embryo using reproductive biotechnology such as IVM/IVF, ICSI and nuclear transfer may cause abnormal epigenetic pattern. This review summarise the role and the importance of epigenetic in embryonic development as well as reproductive biotechnology from research literature mainly in mouse used as a model for mammalian development.