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Author: Anunchai Assawamakin

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    An omnibus permutation test on ensembles of two-locus analyses for the detection of purely epistatic multi-locus interactions
    (2009-12-01) Waranyu Wongseree; Anunchai Assawamakin; Theera Piroonratana; Saravudh Sinsomros; Chanin Limwongse; Nachol Chaiyaratana; King Mongkut's University of Technology North Bangkok; Mahidol University
    for the epistasis detection. However, exhaustive multi-locus analysis requires prohibitively large computational efforts when problems involve large-scale or genome-wide data. Furthermore, there is no explicit proof that a combination of multiple two-locus analyses... can lead to the correct identification of multi-locus interactions. 2LOmb which performs an omnibus permutation test on ensembles of two-locus analyses is proposed. The algorithm consists of four main steps: two-locus analysis, a permutation test