Search Results

Now showing 1 - 6 of 6
  • Publication
    An integrated bioinformatics approach to the characterization of influenza A/H5N1 viral sequences by microarray data: Implication for monitoring H5N1 emerging strains and designing appropriate influenza vaccines
    (2010-12-01) Supaporn Kaewpongsri; Chonlaphat Sukasem; Chutatip Srichunrusami; Ekawat Pasomsub; Julien Zwang; Wantanit Pairoj; Wasun Chantratita; Mahidol University; Shoklo Malaria Research Unit
    pathogenic H5N1 viral isolations were collected from different areas of Thailand between 2003 and 2006, and were used for analysis of H5N1 genotypic testing with a semiconductor-based oligonucleotide microarray. All H5N1 samples and H1N1, H4N8 negative....89). Semi-conductor-based oligonucleotide array and oligonucleotide probes corresponded well when detecting H5N1. After fully correcting the subtype from the result of microarray signal intensity, the microarray output method combined with bioinformatics
  • Publication
    Impact of cyp2d6 polymorphisms on tamoxifen responses of women with breast cancer: A microarray-based study in thailand
    (2012-01-01) Chonlaphat Sukasem; Ekaphop Sirachainan; Montri Chamnanphon; Khunthong Pechatanan; Thitiya Sirisinha; Touch Ativitavas; Ravat Panvichian; Vorachai Ratanatharathorn; Narumol Trachu; Wasun Chantratita; Division of Pharmacogenomics and Personalized Medicine; Division of Virology; Division of Gynecologic Oncology; Mahidol University
    patients who received adjuvant tamoxifen for evaluating CYP2D6 genetic polymorphisms using microarray-based technology. Associations between genotypes-phenotypes and disease free survival were analyzed. Median follow up time was 5.6 years. The mean age
  • Publication
    UGT1A1 polymorphisms associated with prolactin response in risperidone-treated children and adolescents with autism spectrum disorder
    (2018-12-01) Yaowaluck Hongkaew; Sadeep Medhasi; Ekawat Pasomsub; Nattawat Ngamsamut; Apichaya Puangpetch; Natchaya Vanwong; Monpat Chamnanphon; Penkhae Limsila; Chuthamanee Suthisisang; Bob Wilffert; Chonlaphat Sukasem; Mae Fah Luang University; Faculty of Medicine, Ramathibodi Hospital, Mahidol University; Thailand Ministry of Public Health; Mahidol University; University of Groningen; University of Groningen, University Medical Center Groningen
    GeneChip microarray platform. Genotypes of SNPs used to test the accuracy of DMET genotype profiling were determined using TaqMan SNP Genotyping Assay kits. Eighty-four patients were selected for the allelic association study after microarray analyses... microarray platform, we found three UGT1A1 variants with suggestive evidences of association with the risperidone-induced prolactin response both measured by hyperprolactinemia and by prolactin level. However, due to the lack of validation studies
  • Publication
    Importance of pharmacogenetics in the treatment of children with attention deficit hyperactive disorder: A case report
    (2013-01-10) Teerarat Tan-kam; Chutamanee Suthisisang; Chosita Pavasuthipaisit; Penkhae Limsila; Apichaya Puangpetch; Chonlaphat Sukasem; Thailand Ministry of Public Health; Mahidol University
    appetite. The All-In-One PGX (All-In-One Pharmacogenetics for Antipsychotics test for CYP2D6, CYP2C19, and CYP2C9) was performed using microarray-based and real-time polymerase chain reaction techniques. The genotype of our patient was identified to be CYP2
  • Publication
    Whole-Exome Sequencing Identifies One de Novo Variant in the FGD6 Gene in a Thai Family with Autism Spectrum Disorder
    (2018-01-01) Chuphong Thongnak; Areerat Hnoonual; Duangkamol Tangviriyapaiboon; Suchaya Silvilairat; Apichaya Puangpetch; Ekawat Pasomsub; Wasun Chantratita; Pornprot Limprasert; Chonlaphat Sukasem; Faculty of Medicine, Prince of Songkia University; King Mongkut's Institute of Technology Ladkrabang; Vajira Hospital; Faculty of Medicine, Ramathibodi Hospital, Mahidol University; Prince of Songkla University; Chiang Mai University; Rajanagarindra Institute of Child Development
    © 2018 Chuphong Thongnak et al. Autism spectrum disorder (ASD) has a strong genetic basis, although the genetics of autism is complex and it is unclear. Genetic testing such as microarray or sequencing was widely used to identify autism markers
  • Publication
    CYP2C19 polymorphisms in the Thai population and the clinical response to clopidogrel in patients with atherothrombotic-risk factors
    (2013-08-28) Chonlaphat Sukasem; Ramaimon Tunthong; Montri Chamnanphon; Siwalee Santon; Thawinee Jantararoungtong; Napatrupron Koomdee; Santirhat Prommas; Apichaya Puangpetch; Prin Vathesatogkit; Mahidol University
    in this study. Genotypes for CYP2C19 polymorphisms were detected by the microarray-based technique. Furthermore, results of genotyping and platelet aggregation in 96 cardiovascular disease patients on 75 mg clopidogrel maintenance daily dose therapy also were