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Item Metadata only Metabolic sensor O-GlcNAcylation regulates erythroid differentiation and globin production via BCL11A(2022-12-01) Luanpitpong S.; Kang X.; Janan M.; Thumanu K.; Li J.; Kheolamai P.; Issaragrisil S.; Mahidol Universityhas not been addressed. Methods: Cellular O-GlcNAcylation was manipulated using small molecule inhibition or CRISPR/Cas9 manipulation of catalyzing enzyme O-GlcNAc transferase (OGT) and removing enzyme O-GlcNAcase (OGA) in two cell models of erythroidItem Metadata only Role of YAP in hematopoietic differentiation and erythroid lineage specification of human-induced pluripotent stem cells(2023-09-29) Laowtammathron C.; Lorthongpanich C.; Jiamvoraphong N.; Srisook P.; Klaihmon P.; Kheolamai P.; Luanpitpong S.; Issaragrisil S.; Mahidol Universityhematopoietic differentiation, and promoting the differentiation toward endothelial lineage. CONCLUSIONS: Expression of YAP is crucial for the differentiation of hiPSC-derived HSPCs toward mature erythrocytes. We believe that by manipulating YAP activity using