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Publication Metadata only Ventilation management in acute respiratory failure related to COVID-19 versus ARDS from another origin–a descriptive narrative review(2021-01-01) Anissa M. Tsonas; Michela Botta; Ary Serpa Neto; Janneke Horn; Frederique Paulus; Marcus J. Schultz; Melbourne Medical School; Hogeschool van Amsterdam, University of Applied Sciences; University of Melbourne; Hospital Israelita Albert Einstein; Faculty of Medicine, Nursing and Health Sciences; Mahidol University; Nuffield Department of Medicine; Amsterdam UMC - University of Amsterdam; Amsterdam UMCIntroduction: It is uncertain whether ventilation in patients with acute respiratory failure related to coronavirus disease 2019 (COVID-19) differs from that in patients with acute respiratory distress syndrome (ARDS) from another origin. Areas... covered: We undertook two literature searches in PubMed to identify observational studies reporting on ventilation management––one in patients with acute respiratory failure related to COVID-19, and one in patients with ARDS from another originPublication Metadata only ERS statement on chest imaging in acute respiratory failure(2019-09-01) Davide Chiumello; Giuseppe Francesco Sferrazza Papa; Antonio Artigas; Belaid Bouhemad; Aleksandar Grgic; Leo Heunks; Klaus Markstaller; Giulia M. Pellegrino; Lara Pisani; David Rigau; Marcus J. Schultz; Giovanni Sotgiu; Peter Spieth; Maurizio Zompatori; Paolo Navalesi; Université Bourgogne Franche-Comté; IRCCS Multimedica; Dresden International University; Università degli studi Magna Graecia di Catanzaro; Università degli Studi di Milano; Alma Mater Studiorum Università di Bologna; Dresden University Faculty of Medicine and University Hospital Carl Gustav Carus; Universitätsklinikum des Saarlandes Medizinische Fakultät der Universität des Saarlandes; Universitat Autònoma de Barcelona; Ospedale San Paolo; Mahidol University; Medizinische Universitat Wien; Università degli Studi di Sassari; Vrije Universiteit Amsterdam; University Hospitals Sagrado Corazon - General de Cataluna; Casa di Cura del PoliclinicoCopyright ©ERS 2019. Chest imaging in patients with acute respiratory failure plays an important role in diagnosing, monitoring and assessing the underlying disease. The available modalities range from plain chest X-ray to computed tomography, lung... of the present European Respiratory Society (ERS) statement is to provide physicians with a comprehensive clinical review of chest imaging techniques for the assessment of patients with acute respiratory failure, based on the scientific evidence as identifiedPublication Metadata only Pragmatic recommendations for the management of acute respiratory failure and mechanical ventilation in patients with COVID-19 in low- And middle-income countries(2021-03-01) Ary Serpa Neto; William Checkley; Chaisith Sivakorn; Madiha Hashmi; Alfred Papali; Marcus J. Schultz; Faculty of Tropical Medicine, Mahidol University; University of Melbourne; Monash University; Hospital Israelita Albert Einstein; Mahidol University; Nuffield Department of Medicine; Amsterdam UMC - University of Amsterdam; Johns Hopkins School of Medicine; Division of Pulmonary and Critical Care Medicine; Ziauddin Medical Collegeon a set of pragmatic recommendations for acute respiratory failure and mechanical ventilation management in patients with severe/critical COVID-19 in LMICs. We suggest starting supplementary oxygen when SpO2 is persistently lower than 94%. We recommend...Management of patients with severe or critical COVID-19 is mainly modeled after care for patients with severe pneumonia or acute respiratory distress syndrome (ARDS) from other causes, and these recommendations are based on evidence that oftenPublication Metadata only Optimizing respiratory management in resource-limited settings(2019-02-01) Rebecca Inglis; Emmanuel Ayebale; Marcus J. Schultz; Makerere University; University of Oxford; Mahidol University; Royal Liverpool and Broadgreen University Hospitals NHS Trust; Amsterdam UMC - University of Amsterdam; Mahosot HospitalPURPOSE OF REVIEW: This review focuses on the emerging body of literature regarding the management of acute respiratory failure in low- and middle-income countries (LMICs). The aim is to abstract management principles that are of relevance across a... with acute respiratory failure and trials suggest that noninvasive ventilation can be conducted safely in settings where resources are low. SUMMARY: The management of patients with acute respiratory failure in LMICs should focus on avoiding intubation wherePublication Metadata only Mucoactive agents for acute respiratory failure in the critically ill: A systematic review and meta-analysis(2020-08-01) Rohan Anand; Daniel F. McAuley; Bronagh Blackwood; Chee Yap; Brenda Oneill; Bronwen Connolly; Mark Borthwick; Murali Shyamsundar; John Warburton; David Van Meenen; Frederique Paulus; Marcus J. Schultz; Paul Dark; Judy M. Bradley; Faculty of Biology, Medicine and Health; Oxford University Hospitals NHS Foundation Trust; Bristol Royal Infirmary; Queen's University Belfast; University of Melbourne; Ulster University; Mahidol University; Nuffield Department of Medicine; Guy's and St Thomas' NHS Foundation Trust; Universiteit van Amsterdam© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Purpose Acute respiratory failure (ARF) is a common cause of admission to intensive care units (ICUsPublication Metadata only Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method(2021-12-01) Prashant Nasa; Elie Azoulay; Ashish K. Khanna; Ravi Jain; Sachin Gupta; Yash Javeri; Deven Juneja; Pradeep Rangappa; Krishnaswamy Sundararajan; Waleed Alhazzani; Massimo Antonelli; Yaseen M. Arabi; Jan Bakker; Laurent J. Brochard; Adam M. Deane; Bin Du; Sharon Einav; Andrés Esteban; Ognjen Gajic; Samuel M. Galvagno; Claude Guérin; Samir Jaber; Gopi C. Khilnani; Younsuck Koh; Jean Baptiste Lascarrou; Flavia R. Machado; Manu L.N.G. Malbrain; Jordi Mancebo; Michael T. McCurdy; Brendan A. McGrath; Sangeeta Mehta; Armand Mekontso-Dessap; Mervyn Mer; Michael Nurok; Pauline K. Park; Paolo Pelosi; John V. Peter; Jason Phua; David V. Pilcher; Lise Piquilloud; Peter Schellongowski; Marcus J. Schultz; Manu Shankar-Hari; Suveer Singh; Massimiliano Sorbello; Ravindranath Tiruvoipati; Andrew A. Udy; Tobias Welte; Sheila N. Myatra; Narayana Superspeciality Hospital, Gurugram; Faculty of Biology, Medicine and Health; Université Paris Cité; Manchester University NHS Foundation Trust; Université de Montpellier; IRCCS San Martino Polyclinic Hospital; Université de Lyon; King Saud bin Abdulaziz University for Health Sciences; Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Erasmus MC; McMaster University; Centre Hospitalier Universitaire de Montpellier; Royal Adelaide Hospital; Wake Forest University School of Medicine; National University Hospital; Pontificia Universidad Católica de Chile; CHU de Nantes; University of Oxford; Vrije Universiteit Brussel; University of Michigan, Ann Arbor; Università degli Studi di Genova; Hôpital Henri Mondor; Centre Hospitalier Universitaire Vaudois; Shaare Zedek Medical Center; Monash University; Tata Memorial Hospital; Hopital Edouard Herriot; University of Toronto; University of the Witwatersrand, Johannesburg; Cedars-Sinai Medical Center; Universidade Federal de São Paulo; University of Maryland School of Medicine; Mahidol University; Hospital Universitari de Bellvitge; Vagelos College of Physicians and Surgeons; King's College London; Medizinische Universität Wien; Peking Union Medical College Hospital; University of Ulsan College of Medicine; Mayo Clinic; Guy's and St Thomas' NHS Foundation Trust; Royal Melbourne Hospital; Hospital Universitario de Getafe; Chelsea and Westminster Hospital; Amsterdam UMC - University of Amsterdam; Gandhi Medical College; Christian Medical College, Vellore; University of Maryland; A.O.U. Policlinico-San Marco; Regency Super Speciality Hospital; International Fluid Academy; German Center for Lung Research; Max Super Speciality Hospital; Columbia Asia Referral Hospital; PSRI Hospital; NMC Speciality HospitalBackground: Coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented pressure on healthcare system globally. Lack of high-quality evidence on the respiratory management of COVID-19-related acute respiratory failure (C-ARF) has resulted...-square (χ2) test (p < 0·05 was considered as unstable). Results: Agreement was achieved for 27 (73%) management strategies which were then used to develop expert clinical practice statements. Experts agreed that COVID-19-related acute respiratory distressPublication Metadata only Awake proning as an adjunctive therapy for refractory hypoxemia in non-intubated patients with COVID-19 acute respiratory failure: Guidance from an international group of healthcare workers(2021-05-05) Willemke Stilma; Eva Åkerman; Antonio Artigas; Andrew Bentley; Lieuwe D. Bos; Thomas J.C. Bosman; Hendrik De Bruin; Tobias Brummaier; Laura A. Buiteman-Kruizinga; Francesco Carcò; Gregg Chesney; Cindy Chu; Paul Dark; Arjen M. Dondorp; Harm J.H. Gijsbers; Mary Ellen Gilder; Domenico L. Grieco; Rebecca Inglis; John G. Laffey; Giovanni Landoni; Weihua Lu; Lisa M.N. Maduro; Rose McGready; Bairbre McNicholas; Diego De Mendoza; Luis Morales-Quinteros; Francois Nosten; Alfred Papali; Gianluca Paternoster; Frederique Paulus; Luigi Pisani; Eloi Prud'Homme; Jean Damien Ricard; Oriol Roca; Chiara Sartini; Vittorio Scaravilli; Marcus J. Schultz; Chaisith Sivakorn; Peter E. Spronk; Jaques Sztajnbok; Youssef Trigui; Kathleen M. Vollman; Margaretha C.E. Van Der Woude; Facoltà di Medicina e Chirurgia; Faculty of Tropical Medicine, Mahidol University; Faculty of Biology, Medicine and Health; Université Paris Cité; Manchester University NHS Foundation Trust; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias; Ospedale San Carlo, Potenza; Gelre Ziekenhuizen; Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Instituto de Infectologia Emilio Ribas; University Hospital Galway; Università Cattolica del Sacro Cuore, Campus di Roma; University of Oxford; Wannan Medical College; NYU Grossman School of Medicine; IRCCS Ospedale San Raffaele; Universitat Autònoma de Barcelona; Karolinska Universitetssjukhuset; University of Maryland School of Medicine; Hospital Universitari Vall d'Hebron; Karolinska Institutet; Hospital Universitari de Bellvitge; Nuffield Department of Medicine; Hospital de Sabadell; NUI Galway; Ospedale Maggiore Policlinico Milano; AP-HM Assistance Publique - Hôpitaux de Marseille; The University of Manchester; Hopital Louis-Mourier; Universiteit van Amsterdam; Amsterdam UMC - University of Amsterdam; Chiang Mai University; Reinier de Graaf Hospital - SSDZ; Research Section; Zuyderland Medisch Centrum; Advancing Nursing LLC; Centre Hospitalier d'Aix-en-Provence; Division of Pulmonary and Critical Care MedicineNon-intubated patients with acute respiratory failure due to COVID-19 could benefit from awake proning. Awake proning is an attractive intervention in settings with limited resources, as it comes with no additional costs. However, awake proning... treatment for hypoxemia refractory to supplemental oxygen, seems safe in non-intubated patients with COVID-19 acute respiratory failure. We provide pragmatic recommendations including indications and contraindications for the use of awake proning in LMICs.Publication Metadata only Pragmatic recommendations for the prevention and treatment of acute kidney injury in patients with COVID-19 in low- And middle-income countries(2021-03-01) Kristina E. Rudd; Elif A. Cizmeci; Gabriela M. Galli; Ganbold Lundeg; Marcus J. Schultz; Alfred Papali; Mongolian National University of Medical Sciences; University of Toronto; Mahidol University; Nuffield Department of Medicine; University of Pittsburgh School of Medicine; University Medical Center Amsterdam; Division of Pulmonary and Critical Care Medicinewith COVID-19 in LMICs, we recommend using isotonic crystalloid solutions for expansion of intravascular volume, avoiding nephrotoxic medications, and using a conservative fluid management strategy in patients with respiratory failure. For the diagnosis... and COVID-19 in LMICS, we recommend judicious use of intravenous fluid resuscitation. For patients requiring dialysis who do not have acute respiratory distress syndrome (ARDS), we suggest using peritoneal dialysis (PD) as first choice, where availablePublication Metadata only Association of intensity of ventilation with 28-day mortality in COVID-19 patients with acute respiratory failure: insights from the PRoVENT-COVID study(2021-12-01) Michiel T.U. Schuijt; Marcus J. Schultz; Frederique Paulus; Ary Serpa Neto; J. P. van Akkeren; A. G. Algera; C. K. Algoe; R. B. van Amstel; O. L. Baur; P. van de Berg; D. C.J.J. Bergmans; D. I. van den Bersselaar; F. A. Bertens; A. J.G.H. Bindels; M. M. de Boer; S. den Boer; L. S. Boers; M. Bogerd; L. D.J. Bos; M. Botta; J. S. Breel; H. de Bruin; S. de Bruin; C. L. Bruna; L. A. Buiteman-Kruizinga; O. Cremer; R. M. Determann; W. Dieperink; D. A. Dongelmans; H. S. Franke; M. S.Galek Aldridge; M. J. de Graaff; L. A. Hagens; J. J. Haringman; N. F.L. Heijnen; S. Hiel; S. T. van der Heide; P. L.J. van der Heiden; L. L. Hoeijmakers; L. Hol; M. W. Hollmann; M. E. Hoogendoorn; J. Horn; R. van der Horst; E. L.K. Ie; D. Ivanov; N. P. Juffermans; E. Kho; E. S. de Klerk; A. W.M. Koopman; M. Koopmans; S. Kucukcelebi; M. A. Kuiper; D. W. de Lange; D. M. van Meenen; Ignacio Martin-Loeches; Guido Mazzinari; N. van Mourik; S. G. Nijbroek; M. Onrust; E. A.N. Oostdijk; F. Paulus; C. J. Pennartz; J. Pillay; L. Pisani; I. M. Purmer; T. C.D. Rettig; J. P. Roozeman; M. J. Schultz; A. Serpa Neto; M. E. Sleeswijk; M. R. Smit; P. E. Spronk; W. Stilma; A. C. Strang; A. M. Tsonas; P. R. Tuinman; C. M.A. Valk; F. L. Veen; A. P.J. Vlaar; L. I. Veldhuis; P. van Velzen; W. H. van der Ven; P. van Vliet; P. van der Voort; H. H. van der Wier; L. van Welie; H. J.F.T. Wesselink; B. van Wijk; T. Winters; W. Y. Wong; A. R.H. van Zanten; Hogeschool van Amsterdam, University of Applied Sciences; Monash University; Mahidol University; Nuffield Department of Medicine; Amsterdam UMC - University of Amsterdamif a similar association exists in coronavirus disease 2019 (COVID-19) patients with acute respiratory failure. Methods: We aimed to investigate the impact of intensity of ventilation on patient outcome. The PRoVENT-COVID study is a national multicenter... ventilated COVID-19 patients with acute respiratory failure, we show an independent association of MP, but not ΔP with 28-day mortality. MP could serve as one prognostic biomarker in addition to ΔP in these patients. Efforts aiming at limiting both ΔP and MPPublication Metadata only Lung microbiota predict clinical outcomes in critically ill patients(2020-03-01) Robert P. Dickson; Marcus J. Schultz; Tom Van Der Poll; Laura R. Schouten; Nicole R. Falkowski; Jenna E. Luth; Michael W. Sjoding; Christopher A. Brown; Rishi Chanderraj; Gary B. Huffnagle; Lieuwe D.J. Bos; University of Michigan Medical School; Mahidol University; Universiteit van Amsterdam; Amsterdam UMC - University of Amsterdam; Michigan Center for Integrative Research in Critical Carein critical illness and represents a novel therapeutic target for the prevention and treatment of acute respiratory failure.... bacteria predicted ventilator-free days (P = 0.003), driven by the presence of gutassociated bacteria (e.g., species of the Lachnospiraceae and Enterobacteriaceae families). Detection of gut-associated bacteria was also associated with the presence of acute