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Publication Metadata only Nitric oxide and aggressive behavior of lung cancer cells(2015-01-01) Sudjit Luanpitpong; Pithi Chanvorachote; Mahidol University; Chulalongkorn Universitymicroenvironment. In lung cancer, a high level of NO is linked to advanced stage and poor survival of patients. This review describes the promotory role of NO in aggressive behavior of lung cancer cells with a focus on apoptosis and anoikis resistance, cell... these changes could affect aggressive behavior. Such knowledge will encourage additional experimental and clinical investigations that contribute to the understanding of the molecular basis of cancer pathophysiology which could lead to targeted cancer therapy.Publication Metadata only Iron induces cancer stem cells and aggressive phenotypes in human lung cancer cells(2016-01-01) Pithi Chanvorachote; Sudjit Luanpitpong; Chulalongkorn University; Mahidol Universityof how CSCs are regulated is still limited. Redox status of the cells has been shown to dramatically influence cell signaling and CSC-like aggressive behaviors. Here, we investigated how subtoxic concentrations of iron, which have been found... regulation and its importance in aggressive cancer behaviors and likely metastasis through SOX9 upregulation.Publication Metadata only Inhibition of O-GlcNAcase sensitizes apoptosis and reverses bortezomib resistance in mantle cell lymphoma through modification of truncated bid(2018-02-01) Sudjit Luanpitpong; Nawin Chanthra; Montira Janan; Jirarat Poohadsuan; Parinya Samart; Yaowalak U-Pratya; Yon Rojanasakul; Surapol Issaragrisil; West Virginia University; Mahidol University; Faculty of Medicine, Siriraj Hospital, Mahidol University; Wattanosoth Hospital© 2017 AACR. Aberrant energy metabolism represents a hallmark of cancer and contributes to numerous aggressive behaviors of cancer cells, including cell death and survival. Despite the poor prognosis of mantle cell lymphoma (MCL), due