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Item Metadata only Studies of biological significance of apoptosis upon white-spot syndrome virus infection in penaeid shrimp(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Anchukorn Rijiravanich; Boonsirm WithyachumnarnkulItem Metadata only The role of non-neuronal cholinergic components in leukemogenesis(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Sadudee Chotirat; Chirayu Auewarakul; Wanna Thongnoppakhun; Tawit Suriyoin inducing NB-4 maturation. The combination of carbachol and ATRA treatment resulted in decreased viability as determined by XTT cell viability assay and increased cleaved caspase-3 expression when compared with ATRA treatment alone (p<0.05). However..., this combination did not cause poly (ADP-ribose) polymerase (PARP) cleavage, indicating that carbachol treatment led to apoptosis via caspase-3 activation but not PARP activation. Overall, NB-4 cells expressed M3-mAChR in a differentiation-dependent manner