4 results
Search Results
Now showing 1 - 4 of 4
Item Metadata only In Vitro antimicrobial susceptibilities of Burkholderia Pseudomallei and pharmacokinetics and pharmacokinetics of Ceftazidime in melioidosis patients(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Cheardchai Soontornpas; Sumarn SarayaItem Metadata only Hypoglycemic activities of the extract of Thai traditional herbal formula used in Wang-Nam-Yen Hospital(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Kullacha Chayarop; Rungravi Temsiririrkkul; Penchom Peungvicha; Yuvadee Wongkrajang; Wongsatit Chuakul; Piyanuch Rojsangaand safety of this herbal formula, its in vivo and in vitro hypoglycaemic activity, effect on serum biochemical profiles and acute toxicity were investigated. Aqueous extract of the herbal formula was the most potent extract for improving glucose tolerance... measured by the validated HPLC method. The revealed in vivo and in vitro hypoglycemic activities, beneficial effects to biochemical profiles and non-acute toxicity of the whole formula aqueous extract provided valuable insight for next-steps researchItem Metadata only In silico prediction and simulation for biopharmaceutics of oral piperine using GastroPlus software(Mahidol University. Mahidol University Library and Knowledge Center, 2013) Chatsiri Jesadakultavee; Korbtham Sathirakul; Ariya KhumvichaiThe aims of this study were to predict and develop piperine absorption simulation models by extrapolating in vitro and preclinical animal data to simulate the pharmacokinetic parameters of piperine in rats and humans. In addition, models were built... profile. MDCK cell cultures, solubility testing, allometric scaling, predicted CYP enzyme Vmax, Km, predicted clearance from well-stirred and parallel tube models explained the absorption, distribution, and metabolism of piperine. The predicted valuesItem Metadata only Antioxidative effects of crude water extract of mangosteen in healthy volunteers(Mahidol University. Mahidol University Library and Knowledge Center, 2015) Vatchara Tunrungruangtavee; Primchanien Moongkarndi; Wichit Suthammarakthe in vitro and in vivo results, the protective effect of crude water extract of mangosteen (CWM) was obtained as described. Then, the aim of this study was to evaluate the safety of CWM in healthy volunteers and also determine the markers involving oxidative... mg with corn starch. In this study, we have attempted to determine the properties of CWM after preparation, which consisted of two parts. The first part, we checked the overall quality of CWM capsules on a weight variation test, disintegration test