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Item Metadata only Factors contributing to reduced red blood cell deformability in severe falciparum malaria(Mahidol University. Mahidol University Library and Knowledge Center, 2005) Forradee Nuchsongsin; Kesinee ChotivanichThe reduction of red cell deformability in infected and uninfected red blood cells was observed in malaria patients. It was hypothesized that reduction of red cell deformability may be caused by free radical damage from oxidative stress.... The parasite's hemoglobin degradation was the source of oxidative stress. This process produced free radical, oxidizing agents and pro-oxidizing agents when the schizonts ruptured. These free radicals and oxidizing agents attack the red cell membrane it lead
