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Publication Metadata only Cost-Effectiveness Analysis of Non-Statin Lipid-Modifying Agents for Secondary Cardiovascular Disease Prevention Among Statin-Treated Patients in Thailand(2019-10-01) Khachen Kongpakwattana; Zanfina Ademi; Thanaputt Chaiyasothi; Surakit Nathisuwan; Ella Zomer; Danny Liew; Nathorn Chaiyakunapruk; University of Utah; Monash University; Monash University Malaysia; Mahidol University; Srinakharinwirot University© 2019, Springer Nature Switzerland AG. Background: Using non-statin lipid-modifying agents in combination with statin therapy provides additional benefits for cardiovascular disease (CVD) risk reduction, but their value for money has only been... the cost effectiveness of non-statin agents in statin-treated patients with a history of CVD. Methods: A published Markov model was adopted to investigate lifetime outcomes: (1) number of recurrent CVD events prevented, (2) quality-adjusted life-yearsPublication Metadata only Antiparasitic properties of cardiovascular agents against human intravascular parasite schistosoma mansoni(2021-07-01) Raquel Porto; Ana C. Mengarda; Rayssa A. Cajas; Maria C. Salvadori; Fernanda S. Teixeira; Daniel D.R. Arcanjo; Abolghasem Siyadatpanah; Maria de Lourdes Pereira; Polrat Wilairatana; Josué de Moraes; Faculty of Tropical Medicine, Mahidol University; Universidade Guarulhos; Universidade Federal do Piauí; Birjand University of Medical Sciences; CICECO – Instituto de Materiais de Aveiro; Universidade de São Paulofor new anthelmintic agents. Adopting a phenotypic drug screening strategy, here, we evaluated the antiparasitic properties of 46 commercially available cardiovascular drugs against S. mansoni. From these screenings, we found that amiodarone, telmisartan... in early infection than praziquantel, demonstrating the potential role of this cardiovascular drug as an antischistosomal agent.Publication Metadata only Cardiovascular actions of capsaicinoid extract from Thai capsicum(1998) Pranee Jaiarj; Sithiporn Saichompoo; Yuvadee Wongkrajang; Noppakhun Vongswan; Penchom Peungvicha; Weena Jiratchariyakul; ปราณี ใจอาจ; นพคุณ วงษ์สวรรค์; เพ็ญโฉม พึ่งวิชา; วีณา จิรัจฉริยากูล; ยุวดี วงษ์กระจ่าง; Mahidol University. Faculty of Dentistry. Department of Physiology and Biochemistry; Mahidol University. Faculty of Pharmacy. Department of Physiologyin Thailand and to study the cardiovascular actions of the extract on rat aorta, platelet aggregation, skin blood flow as well as skin irritation in comparison with capsaicin. Formulation of a capsaicinoid cream and test for its effect on skin blood flow... in healthy volunteers were also performed. It was found that the extraction of capsaicinoids using dichloromethane, followed by column chromatography eluted with dichloromethane and methanol (98:2) yielded 2.6% capsaicinoids. Cardiovascular studies on bloodPublication Metadata only Regulatory effect of Phikud Navakot extract on HMG-CoA reductase and LDL-R: Potential and alternate agents for lowering blood cholesterol(2018-09-24) Napatara Tirawanchai; Sudarat Supapornhemin; Anchaleekorn Somkasetrin; Bhoom Suktitipat; Sumate Ampawong; Mahidol University© 2018 The Author(s). Background: For decades, various cardiovascular symptoms have been relieved by the use of Ya-Hom Navakot, which is a formulation comprising 54 herbal medicines. The Thailand Ministry of Public Health listed Ya-Hom Navakot...'s nine active principle and nomenclative herbal ingredients and termed them 'Phikud Navakot' (PN). Several reports have confirmed that PN has cardiovascular benefits similar to Ya-Hom Navakot. However, whether PN facilitates lipid-lowering activityPublication Metadata only Non-steroidal anti-inflammatory drug (NSAID) therapy in patients with hypertension, cardiovascular, renal or gastrointestinal comorbidities: Joint APAGE/APLAR/APSDE/APSH/APSN/PoA recommendations(2020-04-01) Cheuk Chun Szeto; Kentaro Sugano; Ji Guang Wang; Kazuma Fujimoto; Samuel Whittle; Gopesh K. Modi; Chen Huen Chen; Jeong Bae Park; Lai Shan Tam; Kriengsak Vareesangthip; Kelvin K.F. Tsoi; Francis K.L. Chan; Jichi Medical University; National Yang-Ming University Taiwan; Saga University; SungKyunKwan University, School of Medicine; Mahidol University; The University of Adelaide; Chinese University of Hong Kong; Asia-Pacific Society for Digestive Endoscopy (APSDE); Asian Pacific Association of Gastroenterology (APAGE); Asia Pacific League of Associations for Rheumatology (APLAR); Asia Pacific Society of Hypertension (APSH); Asian Pacific Society of Nephrology (APSN); Samarpan Kidney Institute and Research Center; Shanghai Institute of Hypertension© 2020 Author(s). Background Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly prescribed medications, but they are associated with a number of serious adverse effects, including hypertension, cardiovascular disease, kidney... included for the synthesis of evidence-based recommendations. Results Whenever possible, a NSAID should be avoided in patients with treatment-resistant hypertension, high risk of cardiovascular disease and severe chronic kidney disease (CKD). BeforePublication Metadata only Cardiovascular effects of piperine in anaesthesized dogs(1994-01-01) U. Hatthakit; K. K. Shida Pang; P. Piyachaturawat; Mahidol UniversityCardiovascular responses to intravenous administration of piperine were investigated in anaesthetized dogs. Piperine produced biphasic effects on the arterial blood pressure, depressor and pressor effects. In the presence of vagus nerves, low doses.... Verapamil (0.15 mg kg -1 ), a calcium channel blocking agent, completely abolished the overshoot of blood pressure. These results suggest that the depressor effect of piperine is associated with a cholinergic mechanism whereas the pressor effect is relatedPublication Metadata only Anti-thrombotic and Anticoagulant Treatment in Interventional Cardiology(1998-01-01) Nithi Mahanonda; Mahidol Universityagents in cardiovascular field....Efforts to improve Percutaneous Transluminal Coronary Angioplasty (PTCA) have resulted in the usage of new antiplatelets, and antithrombotic agents. These new agents may increase bleeding complications. However, EPIC, EPILOG and CAPTURE trialsPublication Metadata only Roles of pharmacogenomics in non-anthracycline antineoplastic-induced cardiovascular toxicities: A systematic review and meta-analysis of genotypes effect(2019-04-01) Siew Lian Leong; Nathorn Chaiyakunapruk; Wichittra Tassaneeyakul; Poukwan Arunmanakul; Surakit Nathisuwan; Shaun Wen Huey Lee; Taylor's University Malaysia; Cyberjaya University College of Medical Sciences; University of Wisconsin-Madison; Faculty of Medicine, Khon Kaen University; Naresuan University; Monash University Malaysia; Mahidol University; Chiang Mai Universitycardiovascular toxicity in patients treated for cancer of all antineoplastic agents were included except for anthracycline. Case reports, conference abstracts, reviews and non-patient studies were excluded. Data extracted by two independent reviewers were...© 2018 Elsevier B.V. Background: Exploration on genetic roles in antineoplastic-related cardiovascular toxicity has increased with the advancement of genotyping technology. However, knowledge on the extent of genetic determinants in affectingPublication Metadata only Seroprevalence of Chlamydia pneumoniae infection in Thailand(2000-11-01) Wattana Leowattana; Nithi Mahanonda; Kiartuai Bhuripanyo; Sasikarnt Pokum; Mahidol UniversityChlamydia pneumoniae (C. pneumoniae) is an emerging infectious agent, with a spectrum of clinical manifestations, and it has recently been tentatively linked to atherosclerosis. In order to describe the seroprevalence of C. pneumoniae in Thailand... have implications for the prevention of cardiovascular disease if further study concludes that infection with this organism is a risk for cardiovascular disease.Publication Metadata only Selective metabolic effects of salbutamol in anesthetized cats(1976-02-15) Raymond H. Lockwood; Panida Sinkasaem; Mahidol UniversitySalbutamol was found to produce a selective stimulation of beta adrenergic receptors mediating metabolic responses in anesthesized cats. Salbutamol was infused intravenously at a rate of 1 μg/Kg/min; this agent produced a significant decrease... in diastolic blood pressure and concomitantly increased blood glucose and lactate while decreasing plasma potassium. Salbutamol did not elevate plasma free fatty acids. In contrast to salbutamol, comparable infusions of isoproterenol produced all cardiovascular