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Publication Metadata only Eosin B as a novel antimalarial agent for drug-resistant Plasmodium falciparum(2006-09-01) Kristen M. Massimine; Michael T. McIntosh; Lanxuan T. Doan; Chloé E. Atreya; Stephan Gromer; Worachart Sirawaraporn; David A. Elliott; Keith A. Joiner; R. Heiner Schirmer; Karen S. Anderson; Yale University School of Medicine; Universitat Heidelberg; Mahidol University; University of Arizona Medical Center4′,5′-Dibromo-2′,7′-dinitrofluorescein, a red dye commonly referred to as eosin B, inhibits Toxoplasma gondii in both enzymatic and cell culture studies with a 50% inhibitory concentration (IC50) of 180 μM. As a non-active-site inhibitor... of the bifunctional T. gondii dihydrofolate reductase-thymidylate synthase (DHFR-TS), eosin B offers a novel mechanism for inhibition of the parasitic folate biosynthesis pathway. In the present study, eosin B was further evaluated as a potential antiparasiticPublication Metadata only Automated image segmentation of haematoxylin and eosin stained skeletal muscle cross-sections(2013-12-01) F. Liu; A. L. Mackey; R. Srikuea; K. A. Esser; L. Yang; University of Kentucky; Bispebjerg Hospital; Kobenhavns Universitet; Mahidol Universityhaematoxylin and eosin stained slides, is still a manual or semi-automatic process. This procedure is labour-intensive and time-consuming. In this paper, we have developed and validated an automatic image segmentation algorithm that is not only efficient... but also accurate. Our proposed automatic segmentation algorithm for haematoxylin and eosin stained skeletal muscle cross-sections consists of two major steps: (1) A learning-based seed detection method to find the geometric centres of the muscle fibresPublication Metadata only Cytotoxicity screening of anionic dye removal by bio-natural adsorbent: Egg shell and peanut shell(2021-04-01) Parichat Srisamai; Prakaipet Pankaew; Poonnawis Sudtikoonaseth; Niwat Kangwanrangsan; Siriluck Iamtham; Wannee Jiraungkoorskul; Kasetsart University, Kamphaeng Saen Campus; Kasetsart University; Thailand Ministry of Public Health; Mahidol Universityremoval is unknown. The aim of this study was to investigate the toxicity of eosin dye and its removal by adsorbent. Moreover, the cytotoxicity of dye is evaluated by brine shrimp lethality bioassay. The results showed that the dye after removal... by eggshell had the lower mortality rate when compared to those of eosin dye and penut shell adsorption. The histopathological lesions such as abnormal appearance of enterocyte, blebing cell and coagulation necrosis were found. Therefore, these bio-naturalPublication Metadata only Morphology and histology of the adult Paramphistomum gracile Fischoeder, 1901(2013-12-01) Busaba Panyarachun; Arin Ngamniyom; Prasert Sobhon; Panat Anuracpreeda; Srinakharinwirot University; Mahidol University-sections were stained with hematoxylin and eosin, and examined. The body surface and longitudinal section of P. gracile were also assessed using scanning electron microscopy. In this species, the anterior sucker and posterior sucker (acetabulum) werePublication Metadata only Dysplastic nodules and small primary carcinoma of the liver: A study detecting the early morphological changes during hepatocarcinogenesis(2007-02-01) Pattana Sornmayura; Paisan Boonsakan; Abhasnee Sobhonslidsuk; Suthus Sriphojanart; Chakrapan Euanorasetr; Sukhum Bunyaratvej; Mahidol University; Faculty of Medicine, Ramathibodi Hospital, Mahidol Universitythe authors' surgical-pathology file during 2000-2005 for a histopathological study in relevance to the early changes during hepatocarcinogenesis by employing hematoxylin and eosin stain, as well as some immunohistochemical staining. Results: One nodularPublication Open Access Occult Metastases in Negative Sentinel Lymph Node of Invasive Breast Cancer Discovered by Serial Section in Ramathibodi Hospital(2009) Orathai Thangnapakorn; Sansanee Wongwaisayawan; Panuwat Lertsithichai; Sasivimol Rattanasiri; อรทัย ตั้งนภากร; ศันสนีย์ วงศ์ไวศยวรรณ; ภาณุวัฒน์ เลิศสิทธิชัย; ศศิวิมล รัตนสิริ; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Pathology; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Surgery; Mahidol University. Faculty of Medicine Ramathibodi Hospital. Section for Clinical Epidemiology and BiostatisticsBackground: Sentinel lymph node (SLN) biopsy is an established method for evaluating axillary metastases in breast cancer. This study was designed to ascertain whether serial sections with haematoxylin and eosin stain could significant improve... were examined by serial sections at 25 microns intervals at each level with haematoxylin and eosin stain. Result: Occult metastases were detected by serial sectioning in 4 (8%) out of 50 breast cancer patients. One patient had macrometastasis, twoPublication Metadata only Cerebrospinal fluid analysis in eosinophilic meningoencephalitis(2001-12-01) Thanida Tangwanicharoen; Parnpen Viriyavejakul; Benjanee Punpoowong; Polrat Wilairatana; Jaranit Kaewkungwal; Emsri Pongponratn; Mario Riganti; Mahidol Universityreceived specific treatment as supportive therapy, which included spinal taps, analgesics and corticosteroids, was adequate. No fatal cases were seen. The CSF specimens were sorted into two categories: fresh CSF and hematoxylin and eosin (H&E) stainedPublication Metadata only Mast cell activation in the skin of Plasmodium falciparum malaria patients(2015-01-01) Panop Wilainam; Rungrat Nintasen; Parnpen Viriyavejakul; Mahidol University; Huachiew Chalermprakiet Universityuncomplicated and 20 complicated P. falciparum malaria cases. Normal skin tissues from 29 cases served as controls. Pre- and post-treatment tissues were included. Histopathological changes of the skin were evaluated using haematoxylin and eosin stain. MCs werePublication Metadata only Touch imprint cytological analysis of sentinel lymph nodes for detecting axillary metastases in patients with breast cancer(1999-10-25) A. Ratanawichitrasin; C. V. Biscotti; L. Levy; J. P. Crowe; Cleveland Clinic Foundation; Mahidol Universityof sentinel lymph nodes, stained with haematoxylin and eosin. A cytopathologist blinded to the histological results interpreted the smears. Results: The concordance between touch imprint and paraffin sections of sentinel lymph nodes was 98 per cent (54 of 55Publication Metadata only Linburg–Comstock variation: histoanatomy and classification of the connection between flexor pollicis longus and flexor digitorum profundus to the index finger(2018-03-01) Laphatrada Yurasakpong; Krai Meemon; Athikhun Suwannakhan; Mahidol Universitydigitorum profundus to the index finger were identified for the possible occurrence of the intertendinous connection. For histological analysis, selected specimens were sampled, and were stained with hematoxylin and eosin. Results: Out of 130 dissected upper