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Publication Metadata only Predictive SNPs for β0-thalassemia/HbE disease severity(2021-12-01) Thongperm Munkongdee; Sissades Tongsima; Chumpol Ngamphiw; Pongsakorn Wangkumhang; Chayanon Peerapittayamongkol; Hafizah Binti Hashim; Suthat Fucharoen; Saovaros Svasti; Siriraj Hospital; Mahidol University; Institute of Molecular Biosciences, Mahidol University; Thailand National Science and Technology Development Agency; Hospital Sultanah Bahiyahβ-Thalassemia/HbE disease has a wide spectrum of clinical phenotypes ranging from asymptomatic to dependent on regular blood transfusions. Ability to predict disease severity is helpful for clinical management and treatment decision making. A... thalassemia severity score has been developed from Mediterranean β-thalassemia patients. However, different ethnic groups may have different allele frequency and linkage disequilibrium structures. Here, Thai β0-thalassemia/HbE disease genome-wild associationPublication Metadata only Association of dental and periodontal disease with chronic kidney disease in patients of a single, tertiary care centre in Thailand(2016-07-27) R. Ausavarungnirun; S. Wisetsin; N. Rongkiettechakorn; S. Chaichalermsak; U. Udompol; M. Rattanasompattikul; Mahidol University; Saraburi Hospital/1.73 m(2) and brushing teeth more than once a day were associated with hypoalbuminaemia (defined as <3.8 g/dL) (OR (95% CI) 5.88 (1.64 to 21.11), 5.80 (1.58 to 21.35) and 0.16 (0.05 to 0.60), respectively).CONCLUSIONS: Severe periodontal diseases...Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ BACKGROUND: Several studies have shown an associationPublication Metadata only Correlation of lipid peroxidation and glutathione levels with severity of systemic Lupus Erythematosus: A pilot study from single center(2008-12-01) K. Tewthanom; S. Janwityanuchit; K. Totemchockchyakarn; Duangchit Panomvana; Chulalongkorn University; Mahidol Universityfour SLE patients (2 Men and 42 Women) and twenty healthy volunteers (3 Men, 17 women) participated in this study. SLE participants were classified by the severity of disease (mild, moderate or severe). The plasma MDA and plasma Glutathione levels were... measured. The correlation of plasma MDA and plasma GSH levels with the severity of SLE disease were determined. Results. Plasma MDA levels with different severity of SLE (mild, moderate, and severe of SLE patients) were not significantly different fromPublication Metadata only Maternal body mass index at term does not predict the severity of preeclampsia(2008-08-01) Tuangsit Wataganara; Dittakarn Boriboonhirunsarn; Vitaya Titapant; Sujin Kanokpongsakdi; Prasert Sunsaneevithayakul; Chanchai Vantanasiri; Mahidol UniversityObjective: Maternal pre-pregnancy weight is a risk of developing preeclampsia. Whether it is also associated with the disease severity is still elusive. This retrospective cohort was to determine the association between body mass index (BMI) at term... and severity of preeclampsia. Material and Method: BMIs on the delivery date of 229 patients were analyzed with various indicators of the disease severity. The corrected BMI (cBMI), calculated by an exclusion of feto-placental unit, was additionally analyzedPublication Metadata only Prevalence and severity of periodontal disease at mandibular molar teeth in smokers with regular oral hygiene habits(2002-08-27) Varunee Kerdvongbundit; Ulf M.E. Wikesjö; Mahidol UniversityBackground: Smoking appears to be detrimental to health because it has been associated with several diseases including cancer and cardiovascular diseases. Smoking also appears to be a major environmental factor associated with periodontal disease... progression. The objective of this study was to evaluate the prevalence and severity of periodontal destruction as influenced by smoking in a Thai population. Methods: Gingival health and periodontal conditions at mandibular molar furcation sites in 120 ThaiPublication Metadata only The severity of disease measurements among Thai medical intensive care unit patients.(1995-03-01) S. Kiatboonsri; P. Charoenpan; Mahidol UniversitySince the diversity of diseases and complexities of treatment keeps on increasing, a precision of evaluation system that shows a strong and stable relationship to outcomes is needed. The APACHE II severity of disease classification system....5. The actual to predicted death ratio, an indicator of hospital performance, in this studied group was 1.17 and was close to the findings of most centers in USA. By providing a measure of severity of disease, APACHE II classification system can provide ThaiPublication Metadata only Differences in gas exchange between severities of chronic obstructive pulmonary disease(2013-03-01) Wilawan Thirapatarapong; Hilary F. Armstrong; Byron M. Thomashow; Matthew N. Bartels; Columbia University Medical Center; Mahidol UniversityImpaired ventilation on cardiopulmonary exercise test (CPET) is seen in patients with chronic obstructive pulmonary disease (COPD). However, evaluation of the differences of abnormal gas exchange in COPD according to GOLD severity criteria...% was inversely proportional to GOLD severity. Breathing reserve, minute ventilation, and tidal volume at peak exercise were significantly decreased with increasing disease severity between GOLD groups. We concluded that gas exchange is distinctive among differentPublication Metadata only Effect of lifestyle weight loss intervention on disease severity in patients with psoriasis: A systematic review and meta-analysis(2015-08-06) S. Upala; A. Sanguankeo; Columbia University in the City of New York; Mahidol University© 2015 Macmillan Publishers Limited. All rights reserved. Background:Psoriasis is a chronic inflammatory disease of the skin with joint manifestations. Greater psoriasis severity and lower response to treatment have been linked to obesity. However..., the effect of weight reduction by non-pharmacologic intervention on disease severity is still questionable. This is a systematic review and meta-analysis of randomized controlled trials (RCTs) on the effect of dietary and lifestyle weight loss interventionsPublication Metadata only Clinico-pathological correlation of severe tubulointerstitial fibrosis in glomerular diseases(2015-01-01) Nuttasith Larpparisuth; Duangrat Tanratananon; Bunyarit Cheunsuchon; Paisan Parichatikanon; Somkiat Vasuvattakul; Mahidol University© 2015, Medical Association of Thailand. All rights reserved. Background: Renal histopathology is the best method available to assess chronicity of glomerular diseases. However, renal biopsy is an invasive procedure and is available only in medical... schools or tertiary-care hospitals in Thailand. Clinical predictors that discriminate the chronicity index of renal pathology may be valuable for the best timing of biopsy. The authors conducted this study to identify the clinical parameters of severePublication Metadata only Vernal keratoconjunctivitis: A severe allergic eye disease with remodeling changes(2014-01-01) Pakit Vichyanond; Punchama Pacharn; Uwe Pleyer; Andrea Leonardi; Mahidol University; Charité – Universitätsmedizin Berlin; Universita degli Studi di PadovaVernal keratoconjunctivitis (VKC) is an unusually severe sight-threatening allergic eye disease, occurring mainly in children. Conventional therapy for allergic conjunctivitis is generally not adequate for VKC. Pediatricians and allergists are often... not familiar with the severe clinical symptoms and signs of VKC. As untreated VKC can lead to permanent visual loss, pediatric allergists should be aware of the management and therapeutic options for this disease to allow patients to enter clinical remission