Search Results

Now showing 1 - 10 of 3303
  • Item
    Correlation Between Coronavirus Disease 2019 Severity and Noninvasive Assessment of Liver Fibrosis in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease
    (2023-12-01) Tungtrongchitr N.; Srivanitchapoom N.; Hirunpat P.; Sungkanuparph S.; Tungtrongchitr N.; Mahidol University
    Background/Aims: Metabolic dysfunction-associated fatty liver disease is a crucial global health concern. Studies have shown that metabolic dysfunction-associated fatty liver disease patients are at higher risk of severe coronavirus disease 2019.... However, there are no precise measures of the correlation between the degree of metabolic dysfunction-associated fatty liver disease fibrosis and coronavirus disease 2019 severity. This study evaluated the association between metabolic dysfunction
  • Publication
    Predictive SNPs for β0-thalassemia/HbE disease severity
    (2021-12-01) Thongperm Munkongdee; Sissades Tongsima; Chumpol Ngamphiw; Pongsakorn Wangkumhang; Chayanon Peerapittayamongkol; Hafizah Binti Hashim; Suthat Fucharoen; Saovaros Svasti; Siriraj Hospital; Mahidol University; Institute of Molecular Biosciences, Mahidol University; Thailand National Science and Technology Development Agency; Hospital Sultanah Bahiyah
    β-Thalassemia/HbE disease has a wide spectrum of clinical phenotypes ranging from asymptomatic to dependent on regular blood transfusions. Ability to predict disease severity is helpful for clinical management and treatment decision making. A... thalassemia severity score has been developed from Mediterranean β-thalassemia patients. However, different ethnic groups may have different allele frequency and linkage disequilibrium structures. Here, Thai β0-thalassemia/HbE disease genome-wild association
  • Item
    The language of uncertainty in a new illness : hedging and modality in the biomedical discourse of severe acute respiratory syndrome (SARS)
    (Mahidol University. Mahidol University Library and Knowledge Center, 2004) Chavez, Thomas David F.; Luechai Sringernyuang
  • Publication
    Association of dental and periodontal disease with chronic kidney disease in patients of a single, tertiary care centre in Thailand
    (2016-07-27) R. Ausavarungnirun; S. Wisetsin; N. Rongkiettechakorn; S. Chaichalermsak; U. Udompol; M. Rattanasompattikul; Mahidol University; Saraburi Hospital
    /1.73 m(2) and brushing teeth more than once a day were associated with hypoalbuminaemia (defined as <3.8 g/dL) (OR (95% CI) 5.88 (1.64 to 21.11), 5.80 (1.58 to 21.35) and 0.16 (0.05 to 0.60), respectively).CONCLUSIONS: Severe periodontal diseases...Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ BACKGROUND: Several studies have shown an association
  • Item
    A systematic review of circulating IP-10/CXCL10 in patients with Plasmodium infections in relation to disease severity
    (2024-12-01) Kotepui M.; Mahittikorn A.; Masangkay F.R.; Kotepui K.U.; Kotepui M.; Mahidol University
    . This systematic review aimed to collate and critically appraise the current evidence on IP-10 levels in malaria patients. It provided insights into its role in malaria pathogenesis and potential as a biomarker for Plasmodium infections and disease severity... examining the role of IP-10 in patients with Plasmodium infections. A narrative synthesis was applied to summarize key findings and to provide an overview of the relationship between IP-10/CXCL10 levels and Plasmodium infection and disease severity. A total
  • Publication
    Correlation of lipid peroxidation and glutathione levels with severity of systemic Lupus Erythematosus: A pilot study from single center
    (2008-12-01) K. Tewthanom; S. Janwityanuchit; K. Totemchockchyakarn; Duangchit Panomvana; Chulalongkorn University; Mahidol University
    four SLE patients (2 Men and 42 Women) and twenty healthy volunteers (3 Men, 17 women) participated in this study. SLE participants were classified by the severity of disease (mild, moderate or severe). The plasma MDA and plasma Glutathione levels were... measured. The correlation of plasma MDA and plasma GSH levels with the severity of SLE disease were determined. Results. Plasma MDA levels with different severity of SLE (mild, moderate, and severe of SLE patients) were not significantly different from
  • Publication
    Maternal body mass index at term does not predict the severity of preeclampsia
    (2008-08-01) Tuangsit Wataganara; Dittakarn Boriboonhirunsarn; Vitaya Titapant; Sujin Kanokpongsakdi; Prasert Sunsaneevithayakul; Chanchai Vantanasiri; Mahidol University
    Objective: Maternal pre-pregnancy weight is a risk of developing preeclampsia. Whether it is also associated with the disease severity is still elusive. This retrospective cohort was to determine the association between body mass index (BMI) at term... and severity of preeclampsia. Material and Method: BMIs on the delivery date of 229 patients were analyzed with various indicators of the disease severity. The corrected BMI (cBMI), calculated by an exclusion of feto-placental unit, was additionally analyzed
  • Publication
    Prevalence and severity of periodontal disease at mandibular molar teeth in smokers with regular oral hygiene habits
    (2002-08-27) Varunee Kerdvongbundit; Ulf M.E. Wikesjö; Mahidol University
    Background: Smoking appears to be detrimental to health because it has been associated with several diseases including cancer and cardiovascular diseases. Smoking also appears to be a major environmental factor associated with periodontal disease... progression. The objective of this study was to evaluate the prevalence and severity of periodontal destruction as influenced by smoking in a Thai population. Methods: Gingival health and periodontal conditions at mandibular molar furcation sites in 120 Thai
  • Publication
    The severity of disease measurements among Thai medical intensive care unit patients.
    (1995-03-01) S. Kiatboonsri; P. Charoenpan; Mahidol University
    Since the diversity of diseases and complexities of treatment keeps on increasing, a precision of evaluation system that shows a strong and stable relationship to outcomes is needed. The APACHE II severity of disease classification system....5. The actual to predicted death ratio, an indicator of hospital performance, in this studied group was 1.17 and was close to the findings of most centers in USA. By providing a measure of severity of disease, APACHE II classification system can provide Thai
  • Item
    Role of biomarkers in predicting disease severity in acute dengue and SARs-CoV-2-Infected patients
    (2026-12-01) Yamasmith E.; Kinslow J.D.; Berg M.G.; Cloherty G.A.; Moy J.N.; Landay A.L.; Suputtamongkol Y.; Tantibhedhyangkul W.; Yamasmith E.; Mahidol University
    Purpose: The early stages of both dengue infection and COVID-19 can present similarly with acute febrile illness or influenza-like symptoms, and individuals with initially mild disease may progress to more severe symptoms. We performed biomarker... analysis to determine if host immune responses can predict the disease severity of both diseases. Methods: Differential immune response profiles in patient populations were compared during acute dengue or COVID-19 using a panel of 22 soluble biomarkers