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Publication Metadata only Molecular determinants in mussels as biomarkers for environmental stress(2011-02-01) Sutin Kingtong; Tavan Janvilisri; Burapha University; Mahidol Universitypollutant uptake, this paper presents an overview of the significance of the use of molecular biomarkers in mussels as diagnostic and prognostic tools for marine and freshwater pollution monitoring. Biomarkers complement the information of the direct... chemical characterization of different types of contaminants. This review focuses on several types of biomarkers classified according to their functional roles in normal tissues, their respective expression following the exposure to harmful contaminantsPublication Metadata only Source-identifying biomarker ions between environmental and clinical Burkholderia pseudomallei using whole-cell Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS)(2014-06-10) Suthamat Niyompanich; Janthima Jaresitthikunchai; Kitima Srisanga; Sittiruk Roytrakul; Sumalee Tungpradabkul; Mahidol University; Thailand National Center for Genetic Engineering and Biotechnology) with respect to their origins and to further investigate the source-identifying biomarker ions belonging to each bacterial group. The cluster analysis demonstrated that six out of eleven isolates were grouped correctly to their sources. Our results revealed a... total of ten source-identifying biomarker ions, which exhibited statistically significant differences in peak intensity between average environmental and clinical mass spectra using ClinProTools software. Six out of ten mass ions were assignedPublication Metadata only Proteomic and bioinformatic discovery of biomarkers for diabetic nephropathy(2018-03-26) Chadinee Thippakorn; Nalini Schaduangrat; Chanin Nantasenamat; Mahidol Universityof DN are not fully understood and so far, no specific and sufficient diagnostic biomarkers are currently available other than micro- or macroalbuminuria. Therefore, this review describes current and novel protein biomarkers in the context of DN as well... as probable proteins biomarkers associated with pathological processes for the early stage of DN via proteomics data together with bioinformatics. In addition, the mechanisms involved in early development of diabetic vascular disorders and complicationsPublication Metadata only Comparative proteomics of activated THP-1 cells infected with mycobacterium tuberculosis identifies putative clearance biomarkers for tuberculosis treatment(2015-07-27) Benjawan Kaewseekhao; Vivek Naranbhai; Sittiruk Roytrakul; Wises Namwat; Atchara Paemanee; Viraphong Lulitanond; Angkana Chaiprasert; Kiatichai Faksri; Khon Kaen University; Nuffield Department of Clinical Medicine; The Nelson R. Mandela Medical School; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol University©2015 Kaewseekhao et al. Biomarkers for determining clearance of Mycobacterium tuberculosis (Mtb) infection during anti-tuberculosis therapy or following exposure could facilitate enhanced monitoring and treatment.We screened for biomarkers... networks were enriched among the early and sustained infection biomarkers, indicating host-pathogen competition. The BRCA1/2 network was suppressed during infection, suggesting that cell proliferation suppression is a feature of Mtb survival. Our studyPublication Metadata only Modelling the impact and cost-effectiveness of biomarker tests as compared with pathogen-specific diagnostics in the management of undifferentiated fever in remote tropical settings(2016-03-01) Yoel Lubell; Thomas Althaus; Stuart D. Blacksell; Daniel H. Paris; Mayfong Mayxay; Wirichada Pan-Ngum; Lisa J. White; Nicholas P.J. Day; Paul N. Newton; Mahidol University; Nuffield Department of Clinical Medicine; Mahosot Hospital; University of Health Sciencesof either diagnostic tests for specific pathogens or testing for biomarkers of host response that indicate whether antibiotics might be required. The impact and cost-effectiveness of these approaches are relatively unexplored and methods to do so... are not well-developed. Methods: We model the ability of dengue and scrub typhus rapid tests to inform antibiotic treatment, as compared with testing for elevated C-Reactive Protein (CRP), a biomarker of hostinflammation. Using data on causes of fever in ruralPublication Metadata only Synbiotic supplementation improves obesity index and metabolic biomarkers in thai obese adults: A randomized clinical trial(2021-07-01) Chaiyavat Chaiyasut; Bhagavathi Sundaram Sivamaruthi; Periyanaina Kesika; Suchanat Khongtan; Nanticha Khampithum; Subramanian Thangaleela; Sartjin Peerajan; Akkarach Bumrungpert; Khontaros Chaiyasut; Sasithorn Sirilun; Phakkharawat Sittiprapaporn; Chiang Mai Rajabhat University; Mae Fah Luang University; Mahidol University; Dhurakij Pundit University; Chiang Mai University; Health Innovation Instituteis underway to unravel the probable relationship between obesity and intestinal microbiota. Here, we propose a method to understand and elucidate the synergistic function of prebiotics and probiotics in treating obesity. The biomarkers of obesity..., Bifidobacterium breve, inulin, and fructooligosaccharide. The results reveal that the supplementation of synbiotics significantly altered the obesity-associated biomarkers in an appositive way. Further studies are warranted to use synbiotics as an adjuvant therapyItem Metadata only Lipid biomarker profiling of adult Brugia malayi using mass spectrometry detection(2022-09-01) Niyomploy P.; Mangmee S.; Tipthara P.; Saeung A.; Reamtong O.; Sangvanich P.; Mahidol Universityas a biomarker in LF disease. In addition, the lipid profile showed that three membrane lipid classes, glycerophospholipids, glycerolipids and sphingolipids, were discovered. Glycerophospholipids were the main components in adult parasites, especiallyItem Metadata only Proteomic profiling of pig placenta reveals key biomarkers linked to sow reproductive performance(2025-06-01) Harnvoravongchai P.; Phanchana M.; Pholmanee N.; Ladda B.; Thita T.; Ounjai P.; Roytrakul S.; Janvilisri T.; Harnvoravongchai P.; Mahidol Universitybiomarkers for improving sow reproductive performance. Future studies will focus on validating these findings and translating them into practical applications for breeding selection and reproductive management in swine production.Item Metadata only Immunological surveillance using anti-gSG6-P1 IgG biomarker reveals spatio-temporal dynamics of Anopheles exposure and gaps in malaria risk assessment in the Greater Mekong Subregion(2026-01-01) Saeung M.; Jupatanakul N.; Jampeesri N.; Afelt A.; Chareonviriyaphap T.; Manguin S.; Saeung M.; Mahidol UniversityAnopheles gambiae-based anti-salivary biomarker, anti-gSG6-P1, as a serological marker for Anopheles exposure, and examined key entomological, human, and environmental risk factors in Sisaket Province, Thailand. Blood samples were collected via finger prick... behavioral and vector dynamics. These factors highlight key limitations of the anti-gSG6-P1 IgG biomarker in the Greater Mekong Subregion, particularly the lack of well-characterized anti-gSG6-P1 IgG serological response kinetics in regions where predominantItem Metadata only Impact of Mango Puree Supplementation on Inflammatory, Muscle Damage, and Selected T-Cell Biomarkers in Elite Beach Volleyball Players During Regular Training(2026-02-04) Parklak W.; Sawaengwaisayasuk S.; Chaipatpreecha N.; Wanikorn B.; Komindr S.; Munkong N.; Khamros W.; Sangkaew T.; Duangjinda M.; Somnuk S.; Parklak W.; Mahidol Universitybiomarkers, muscle damage, and selected T-cell subsets in Thai men's national beach volleyball players during regular training. Methods: Fifteen male athletes completed a pilot randomized, single-blind, crossover trial. Participants consumed the mango puree....05). Conclusions: Mango puree supplementation during regular training was associated with lower inflammatory and muscle damage biomarkers and alterations in selected T-cell subsets compared with the placebo.