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Item Metadata only A new biomarker panel for differential diagnosis of cholangiocarcinoma: Results from an exploratory analysis(2024-01-01) Köhler B.; Bes M.; Chan H.L.Y.; Esteban J.I.; Piratvisuth T.; Sukeepaisarnjaroen W.; Tanwandee T.; Thongsawat S.; Mang A.; Morgenstern D.; Swiatek-de Lange M.; Dayyani F.; Köhler B.; Mahidol Universityselected combinations and exhaustive search). Results: Overall, 55 CCA, 306 HCC, and 733 CLD control samples were analyzed. For distinguishing CCA from HCC, alpha-fetoprotein and matrix metalloproteinase-2 (MMP-2) showed the best individual performance... two-marker panel, with AUC >90% for all comparisons. Conclusion: MMP-2 and TIMP-1 are promising biomarkers that could support differential diagnosis of CCA. Incorporating these assays into the diagnostic algorithm could provide additional diagnostic
