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  • Publication
    Calcifying cystic odontogenic tumor associated with other lesions: Case report with cone-beam computed tomography findings
    (2012-01-01) Jira Chindasombatjaroen; Sopee Poomsawat; Boworn Klongnoi; Mahidol University
    The calcifying cystic odontogenic tumor (CCOT) simultaneously occurring with other lesions at different locations in the same patient is rare. We report a patient with CCOT associated with an odontoma, a supernumerary tooth, and a dentigerous cyst... simultaneously occurring in the maxilla. Cone-beam computed tomography (CBCT) images showed a welldefined expansile lesion with internal calcification, high-density masses surrounded by low-density area, and a supernumerary tooth at the anterior maxilla
  • Item
    Current Management of Dens Evaginatus Teeth Based on Pulpal Diagnosis
    (2023-01-01) Lerdrungroj K.; Banomyong D.; Songtrakul K.; Porkaew P.; Nakornchai S.; Mahidol University
    Introduction: Dens evaginatus (DE) is a dental anomaly with a supernumerary tubercle projection that typically contains dentin and pulp tissue. However, the tubercle projection can fracture, exposing the dentin and potentially the dental pulp, which... be performed as early as possible by the prep-and-fill technique or the reinforcement technique to preserve tooth vitality and continued root development, with the former reported to be superior compared with the latter. Furthermore, DE teeth with reversible
  • Item
    CACNA1S mutation-associated dental anomalies: A calcium channelopathy
    (2023-01-01) Kantaputra P.; Butali A.; Eliason S.; Chalkley C.; Nakornchai S.; Bongkochwilawan C.; Kawasaki K.; Kumchiang A.; Ngamphiw C.; Tongsima S.; Ketudat Cairns J.R.; Olsen B.; Intachai W.; Ohazama A.; Tucker A.S.; Amendt B.A.; Mahidol University
    with multiple supernumerary cusps, single-cusped premolars, and a reduction in root number. Mutation analysis highlighted a heterozygous c.865A>G; p.Ile289Val mutation in CACNA1S in the patients. CACNA1S is a component of the slowly inactivating L-type voltage...-dependent calcium channel. Mutant protein modeling suggested that the mutation might allow leakage of Ca2+ or other cations, or a tightening, to restrict calcium flow. Immunohistochemistry analysis showed expression of Cacna1s in the developing murine tooth