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Publication Metadata only Screening of pro-apoptotic genes upregulated in an experimental street rabies virus-infected neonatal mouse brain(2005-01-01) Sukathida Ubol; Jitra Kasisith; Dhanesh Pitidhammabhorn; Veera Tepsumethanol; Mahidol University; Thai Red Cross Agency.5-fold difference in their expression levels. These 21 genes can be grouped into two groups, those genes that participate in the commitment phase and those that play a role as executioners. Examples of genes in commitment phase were death receptors (Fas-L... receptor, TNF-receptor), lysosomal proteases, calpain, caspase-1, signaling molecules (ERK, p38MAPK) and bcl-2 family members. Cytochrome c and caspase-3 were representatives of executioners. Based on types of genes activated during the commitment phasePublication Metadata only HIV-vaccine Research and Development in Thailand: Evolution and challenges(2010-05-26) Punnee Pitisuttithum; Kachit Choopanya; Supachai Rerk-Ngnam; Mahidol University; Taksin Hospital; Thailand Ministry of Public HealthThailand has been committed to HIV-Vaccine Research and Development since the launch of its National Plan, in 1993. Series of phase I/II trials, and two phase III clinical trials, have been conducted. The first efficacy trial was conducted with a... into the existing health system, staffing, and commitments. However, there were different issues in recruitment process, follow up, social impact events and community involvement since the target participants were different. © 2009 Elsevier Ltd. All rights reserved.Publication Metadata only Towards malaria elimination in Mpumalanga, South Africa: A population-level mathematical modelling approach(2014-08-03) Sheetal P. Silal; Francesca Little; Karen I. Barnes; Lisa J. White; University of Cape Town; Mahidol University; Nuffield Department of Clinical Medicine© 2014 Silal et al.; licensee BioMed Central Ltd. Background: Mpumalanga in South Africa is committed to eliminating malaria by 2018 and efforts are increasing beyond that necessary for malaria control. Differential Equation models may be used... to study the incidence and spread of disease with an important benefit being the ability to enact exogenous change on the system to predict impact without committing any real resources. The model is a deterministic non-linear ordinary differential equationPublication Metadata only Village-based diagnosis and treatment of malaria(1996-01-01) Kamolnetr Okanurak; Trenton K. Ruebush; Mahidol University; National Center for Infectious DiseasesNetwork of Latin America and the Village Voluntary Malaria Collaborator Program of Thailand. The success of these programs is based on a tradition of active community participation and sustained commitment and support from the national malaria controlPublication Metadata only HIV vaccine research in Thailand: Lessons learned(2008-04-01) Punnee Pitisuttithum; Mahidol UniversityThailand is the only country that has conducted two Phase III efficacy trials and ten other Phase I/II studies using various HIV-1 vaccine constructs. This outstanding record is the result of strong efforts and commitment among various partnersPublication Metadata only Home phototherapy in vitiligo(2017-09-01) Tasneem F. Mohammad; Narumol Silpa-Archa; James L. Griffith; Henry W. Lim; Iltefat H. Hamzavi; Henry Ford Hospital; Mahidol Universityas monotherapy and in combination with other treatment modalities to induce repigmentation. Although phototherapy is safe and effective, its use is limited due to the significant time commitment required and associated costs. Home phototherapy is a safePublication Metadata only Predicting the impact of border control on malaria transmission: a simulated focal screen and treat campaign(2015-07-12) Sheetal P. Silal; Francesca Little; Karen I. Barnes; Lisa J. White; University of Cape Town; Mahidol University; Nuffield Department of Clinical Medicine© 2015 Silal et al. Background: South Africa is one of many countries committed to malaria elimination with a target of 2018 and all malaria-endemic provinces, including Mpumalanga, are increasing efforts towards this ambitious goal. The reductionPublication Metadata only Characterization of -isopropylmalate synthases containing different copy numbers of tandem repeats in Mycobacterium tuberculosis(2009-08-10) Wandee Yindeeyoungyeon; Supaporn Likitvivatanavong; Prasit Palittapongarnpim; Thailand National Center for Genetic Engineering and Biotechnology; Mahidol UniversityAlpha-isopropylmalate synthase (-IPMS) is the key enzyme that catalyzes the first committed step in the leucine biosynthetic pathway. The gene encoding -IPMS in Mycobacterium tuberculosis, leuA, is polymorphic due to the insertion of 57-bp repeatPublication Metadata only Drugs for neglected diseases: A failure of the market and a public health failure?(2001-11-09) Patrice Trouiller; Els Torreele; Piero Olliaro; Nick White; Susan Foster; Dyann Wirth; Bernard Pécoul; Universite Grenoble Alpes; Vrije Universiteit Brussel; Organisation Mondiale de la Sante; Mahidol University; Boston University; Harvard School of Public Health; Medecins Sans Frontieresto address the true health needs of society. This requires political will, a strong commitment to prioritize health considerations over economic interests, and the enforcement of regulations and other mechanisms to stimulate essential drug development. NewPublication Metadata only Modelling malaria elimination on the internet(2011-07-26) Richard J. Maude; Sompob Saralamba; Adrian Lewis; Dean Sherwood; Nicholas J. White; Nicholas Pj Day; Arjen M. Dondorp; Lisa J. White; Mahidol University; Nuffield Department of Clinical Medicine; ISynch-Dwith preliminary optimisation of local malaria elimination strategies before commitment of valuable resources. © 2011 Maude et al; licensee BioMed Central Ltd.
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