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Now showing 1 - 7 of 7
  • Publication
    Vesiculobullous diseases in relation to lupus erythematosus
    (2019-01-01) Suthinee Rutnin; Kumutnart Chanprapaph; Faculty of Medicine, Ramathibodi Hospital, Mahidol University
    . Herein, we thoroughly review the topic of vesiculobullous skin disorders that can be encountered in LE patients and organize them into four groups: LE-specific and aspecific vesiculobullous diseases, LE-related autoimmune bullous diseases, and LE... in association to non-autoimmune conditions. We sought to provide an updated overview highlighting the pathogenesis, clinical, histological, and immunopathological features, laboratory findings, and treatments and prognosis among vesiculobullous conditions in LE.
  • Publication
    Association of HLA and T-cell receptor gene polymorphisms with semple rabies vaccine-induced autoimmune encephalomyelitis
    (1999-01-01) Sucheep Piyasirisilp; Barbara J. Schmeckpeper; Dasnayanee Chandanayingyong; Thiravat Hemachudha; Diane E. Griffin; Johns Hopkins University; The Johns Hopkins School of Medicine; Mahidol University; Chulalongkorn University
    response to myelin basic protein and pathological changes of demyelination in SAE suggest that this disease is the human homologue of experimental autoimmune encephalomyelitis (EAE). SAE and EAE are frequently studied as models for the human demyelinating...Semple rabies vaccine is derived from brain tissue infected with rabies virus that is subsequently inactivated with phenol. Semple rabies vaccine- induced autoimmune encephalomyelitis (SAE) occurs in 1 in 220 immunized individuals. The immune
  • Publication
    Nodular scleroderma in a patient with chronic hepatitis C virus infection: A coexistent or causal infection?
    (2015-01-01) Chayada Kokpol; Emily Y. Chu; Suthinee Rutnin; Mahidol University; University of Pennsylvania, Health System
    the association of HCV infection with systemic autoimmune diseases such as scleroderma....Copyright © Cutis 2015. Nodular scleroderma is a rare form of scleroderma that may occur systemically or locally. The pathogenesis of this variant is unknown. We report the case of a 63-year-old woman with systemic scleroderma and chronic hepatitis
  • Publication
    Association between sarcoidosis, pulse wave velocity, and other measures of subclinical atherosclerosis: a systematic review and meta-analysis
    (2018-10-01) Wai Chung Yong; Anawin Sanguankeo; Sikarin Upala; The University of Chicago; Faculty of Medicine, Siriraj Hospital, Mahidol University; Baystate Franklin Medical Center; The Johns Hopkins School of Medicine
    © 2017, International League of Associations for Rheumatology (ILAR). Chronic inflammation from autoimmune diseases has shown to be a risk factor for atherosclerosis, subsequently leading to cardiovascular disease. Endothelial dysfunction... is the early pathogenesis of atherosclerosis in chronic inflammation, but the risk of atherosclerosis in sarcoidosis is less well defined. This meta-analysis aimed to explore the association of subclinical atherosclerosis and arterial stiffness in sarcoidosis
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    Activation of circulating TFH17 cells associated with activated naive and double negative 2 B cell expansion, and disease activity in systemic lupus erythematosus patients
    (2024-12-01) Khunsri T.; Thawornpan P.; Tianpothong P.; Suangtamai T.; Ngamjanyaporn P.; Leepiyasakulchai C.; Wangriatisak K.; Pisitkun P.; Chootong P.; Khunsri T.; Mahidol University
    Background: Systemic lupus erythematosus (SLE) is the quintessential autoimmune disease, as it is characterized by hyperactivity of CD4+ T cells and subsequently drives lupus pathology. Follicular helper T (TFH) cells play an important role in B... was significantly associated with disease activity score, aNAV, DN2 B cell expansion, and anti-dsDNA antibody level. Thus, the interactions among cTFH1, cTFH17, and B cells likely contribute to the development of autoantibodies and the pathogenesis in SLE.
  • Publication
    Codon72 polymorphism in the p53 tumor suppressor gene in oral lichen planus lesions in a Thai population
    (2010-01-01) Pattamawadee Yanatatsaneeji; Nakarin Kitkumthorn; Chutintorn Dhammawipark; Jierada Rabalert; Vyomesh Patel; Apiwat Mutirangura; Chulalongkorn University; Mahidol University; National Institute of Dental and Craniofacial Research
    Background: Oral lichen planus (OLP) is a T-cell mediated autoimmune disease in which autocytotoxic CD8+ T cells (CTLs) trigger apoptosis of oral epithelial cells. Activated CTLs can produce Fas ligand and by binding to Fas lead to apoptosis... association between the pro/pro genotype and OLP, and that the process of apoptosis, in which p53 plays a role, is a factor in OLP pathogenesis.
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    Candida tropicalis Alters Barrier Permeability and Claudin‑1 Organization in Intestinal Epithelial Cells
    (2025-01-01) Doan H.T.; Chiu Y.L.; Cheng L.C.; Coad R.A.; Chiang H.S.; Doan H.T.; Mahidol University
    Inflammatory bowel disease (IBD) is an autoimmune disorder characterized by chronic inflammation of the gut and compromised intestinal barrier function, resulting from aberrant immune responses targeting the intestinal microbiota. While... the involvement of Candida albicans in IBD pathogenesis is well‑documented, the role of non‑albicans Candida species in IBD remains less understood. Recent studies have identified a correlation between elevated levels of Candida tropicalis, a notable non-albicans