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Publication Metadata only Impact of Serum Bicarbonate Levels on Muscle Mass and Kidney Function in Pre-Dialysis Chronic Kidney Disease Patients(2019-01-01) Piyawan Kittiskulnam; Somrath Srijaruneruang; Adhisabandh Chulakadabba; Nintita Sripaiboonkij Thokanit; Kearkiat Praditpornsilpa; Kriang Tungsanga; Somchai Eiam-Ong; Chulalongkorn University; Faculty of Medicine, Ramathibodi Hospital, Mahidol University; Vichaiyut Medical Centeramong chronic kidney disease (CKD) patients. We conducted a study to test the effects of increased serum bicarbonate level on muscle parameters, nutrition, and renal function in pre-dialysis CKD patients. Methods: This was a randomized, controlled study...© 2019 S. Karger AG, Basel. Copyright: All rights reserved. Background: Treatment of metabolic acidosis to target the higher serum bicarbonate level than guideline recommendation may downregulate muscle protein degradation and improve renal functionPublication Metadata only Oral sodium bicarbonate improves thyroid function in predialysis chronic kidney disease(2010-12-01) Sinee Disthabanchong; Akarapong Treeruttanawanich; Mahidol University; Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityBackground/Aims: Metabolic acidosis (MA) in chronic kidney disease (CKD) associates with protein energy malnutrition, osteoporosis, abnormal endocrine function and increased mortality. Oral sodium bicarbonate has been shown to improve nutritional... on the same medications. Thyroid function tests were measured at baseline and again after 8-12 weeks. Results: All patients had a glomerular filtration rate <35 ml/min/1.73 m2. Serum total CO2 increased significantly in the treatment group and was unchangedPublication Metadata only Prevalence and factors associated with microalbuminuria and abnormal renal function in Thai obese adults(2013-02-01) Supawadee Eiamthanasinchai; Nopparat Laowahutanont; Preyanuj Yamwong; Tanyarat Teerapornlertratt; Mahidol University, family history of obesity, family history of renal disease, smoking, or alcohol drinking; height, weight, body mass index, waist circumference, blood pressure, blood chemistry test and urine analysis were collected. The abnormal function of the kidney...Objective: To determine the prevalence and factors associated with microalbuminuria and abnormal renal function in Thai obese adults. Material and Method: A cross-sectional study data was collected from 86 patients during October 2010 to FebruaryItem Metadata only Integrating Clinical and Histopathological Data to Predict Delayed Graft Function in Kidney Transplant Recipients Using Machine Learning Techniques(2024-12-01) Tirasattayapitak S.; Ratanatharathorn C.; Thotsiri S.; Sutharattanapong N.; Wiwattanathum P.; Arpornsujaritkun N.; Sirisopana K.; Worawichawong S.; Rostaing L.; Kantachuvesiri S.; Tirasattayapitak S.; Mahidol UniversityBackground: Given the significant impact of delayed graft function (DGF) on transplant outcomes, the aim of this study was to develop and validate machine learning (ML) models capable of predicting the risk of DGF in deceased-donor kidney... transplantation (DDKT). Methods: This retrospective cohort study was conducted using clinical and histopathological data collected between 2018 and 2022 at Ramathibodi Hospital from DDKT donors, recipients, and post-implantation time-zero kidney biopsy samplesPublication Metadata only Connective tissue growth factor gene expression and decline in renal function in lupus nephritis(2012-04-01) Chiraporn Tachaudomdach; Surasak Kantachuvesiri; Siribha Changsirikulchai; Surangkana Wimolluck; Koset Pinpradap; Chagriya Kitiyakara; Mahidol University; Faculty of Medicine, Srinakharinwirot UniversityIn lupus nephritis (LN), kidney inflammation may be followed by fibrosis and progressive decline in function. Transforming growth factor (TGF)-β is a notable mediator of fibrosis, but it has other beneficial roles, thus indicating a need... important roles in renal fibrosis, but data are limited in human subjects. The present study tested the hypothesis that renal CTGF mRNA expression is related to TGF-β1 and collagen I expression and is predictive of renal function deterioration in patientsPublication Metadata only Incidence rate and time to occurrence of renal impairment and chronic kidney disease among thai hiv-infected adults with tenofovir disoproxil fumarate use(2021-01-01) Jirayu Visuthranukul; Thanapoom Rattananupong; Phenphop Phansuea; Narin Hiransuthikul; Chulalongkorn University; Police General Hospital; Mahidol UniversityBackground: Tenofovir disoproxil fumarate (TDF) is a major antiretroviral therapy for Thai human immunodeficiency virus (HIV) infected adults. TDF is associated with a decrease in renal function. There is limited data about the use of TDF... with the incidence and time to renal impairment and chronic kidney disease (CKD) in Thai HIV-infected adults. Objectives: To study the association of TDF with the incidence rate and duration of renal impairment and CKD in Thai patients. Methods: A retrospectiveItem Unknown Effectiveness of Program to Slow Progression of Chronic Kidney Disease Among T2DM With HT With CKD 3 in the Community: A Randomized Controlled Trial(2023-01-01) Suvamat J.; Powwattana A.; Thaingtham W.; Pichayapinyo P.; Boonlue S.; Mahidol Universityoutcomes (SBP, DBP, eGFR, BUN, creatinine, albuminuria, FBS, and HbA1c) than the control group (P <.05). In summary, the findings indicate that the program improved clinical outcomes, especially kidney function, effectively slowing the progression of kidney...Chronic kidney disease (CKD) is a significant threat to the quality of life of the global population. Thus, slowing kidney disease progression is considered vital in the treatment of CKD patients. The study aimed to evaluate the effectiveness of aPublication Unknown MRI-based kidney volume measurement in autosomal dominant polycystic kidney disease (ADPKD): Comparison of T2-weighted, ideal, and post-contrast T1-weighted sequences(2020-05-01) P. Wibulpolprasert; N. Tanomsingh; W. Sungkarat; S. Phongkitkarun; B. Phakdeekitcharoen; Faculty of Medicine, Ramathibodi Hospital, Mahidol University© JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND | 2020 Objective: To compare kidney volume (KV) measurements between, single-shot T2-weighted (sshT2W), IDEAL, and post contrast T1-weighted (T1W) images of autosomal dominant polycystic kidney.... Measurements were performed independently by three readers using a method involving manual segmentation with image thresholding. The mean KV differences between the evaluated magnetic resonance imaging (MRI) pulse sequences were compared using paired t-testsItem Unknown Effect of a Low Salt Diet on the Progression of Chronic Kidney Disease: A Prospective, Open-Label, Randomized Controlled Trial(2024-01-01) Trakarnvanich T.; Chailimpamontree W.; Kantachuvesiri S.; Anutrakulchai S.; Manomaipiboon B.; Ngamvitchukorn T.; Suraamornkul S.; Trakarnvanich T.; Kurathong S.; Trakarnvanich T.; Mahidol University, open-label, randomized controlled trial, we examined the impact of a low salt diet on renal function, blood pressure, and other metabolic parameters. Herein, 194 patients with chronic kidney disease (CKD) stages 1 to 3 were randomized in low salt... (intervention) and control groups. The intervention group was provided a low salt diet (1.5 g/day) for 3 months. The control group consumed their usual diet, and daily food intake was recorded in the control group. Renal function tests, 24-h urinary sodiumPublication Metadata only Pre-transplant donor specific antibody and its clinical significance in kidney transplantation(2012-03-01) Duangtawan Thammanichanond; Atiporn Ingsathit; Tasanee Mongkolsuk; Sasivimol Rattanasiri; Surasak Kantachuvesiri; Chulalak Sakhonrat; Charoen Leenanupan; Suchin Worawichawong; Pimpun Kitpoka; Mahidol UniversityThe traditional method for assessing HLA antibodies in recipient serum samples is the complement-dependent cytotoxicity testing (CDC). Recently, the highly sensitive microbead-based Luminex assay was introduced and can detect low levels of anti-HLA... Abs. Objective: To determine the impact of pre-transplant donor-specific HLA antibodies (DSA) detectable by Luminex, despite a negative CDC crossmatch, on the outcomes of kidney transplantation. The correlation and cut-off value of panel reactive