Search Results

Now showing 1 - 3 of 3
  • Publication
    Contribution of prosthetic knee and ankle mechanisms to swing-phase foot clearance
    (2013-01-16) Jonathon W. Sensinger; Nattaporn Intawachirarat; Steven A. Gard; Northwestern University; Mahidol University; Jesse Brown VA Medical Center
    Individuals who ambulate with transfemoral prostheses fall more frequently than users of transtibial prostheses or able-bodied persons. One factor contributing to these falls may be reduced toe clearance during swing phase of the prosthesis.... Quantitative gait data were acquired from ten persons with transfemoral amputations who were fitted with either single-axis or four-bar knees, in a cross-over experiment. Toe clearance during prosthetic swing phase was measured from these trials
  • Publication
    Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Burkina Faso: An open label trial [version 2; peer review: 2 approved]
    (2020-01-01) Sofia Birgersson; Innocent Valea; Halidou Tinto; Maminata Traore-Coulibaly; Laeticia C. Toe; Richard M. Hoglund; Jean Pierre Van Geertruyden; Stephen A. Ward; Umberto D’Alessandro; Angela Abelö; Joel Tarning; Universiteit Gent; London School of Hygiene & Tropical Medicine; Liverpool School of Tropical Medicine; Göteborgs Universitet; Universiteit Antwerpen; Mahidol University; Nuffield Department of Clinical Medicine; Unité de Recherche Clinique de Nanoro; Institut de Recherche en Sciences de la Santé
    pharmacokinetics was best described by a one-compartment disposition model with first-order elimination. Pregnant women had a 21% higher elimination clearance of dihydroartemisinin, compared to non-pregnant women resulting in proportionally lower drug exposure
  • Item
    Footwear for Diabetic Foot Complications
    (2025-01-01) Nouman M.; Nouman M.; Mahidol University
    , offer target offloading for specific patients with neuropathy. It involves ensuring adequate toe clearance, width, depth for insoles, and heel fit. Clinicians must educate patients on incremental wear and daily foot inspection. Optimal footwear balances... effectiveness relies on harmonizing each component with foot anatomy to mitigate abnormal plantar pressure and ulcer risk. Key design features include roomy, extra-depth toe boxes to accommodate deformities, reinforced heel counters for rearfoot stability