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Publication Metadata only Effects of non-spatial pre-training on learning and memory impairment detection in the morris water maze(2018-02-01) Phanit Koomhin; Apsorn Sattayakhom; Sarawoot Palipoch; Chuchard Punsawad; Sompol Tapechum; Walailak University; Faculty of Medicine, Siriraj Hospital, Mahidol University© 2018, Walailak University. All rights reserved. One of the most popular learning and memory tests is the Morris water maze. The Morris water maze is a circular pool filled with water with a hidden platform under the water surface. The test... to leave the water. In the experiment, animals use environmental cues to find the location of the hidden platform in the pool. After consecutive training days, animals can more quickly locate the hidden platform. The last day of the task involves a memoryPublication Metadata only Ceftriaxone improves spatial learning and memory in chronic cerebral hypoperfused rats(2012-12-01) Phanit Koomhin; Kanokwan Tilokskulchai; Sompol Tapechum; Mahidol Universityto permanent bilateral common carotid artery occlusion. Ceftriaxone (200 mg/kg) was injected daily in rats for 5 days after the onset of the arterial ligation. A Morris water maze was used to assess learning and memory two months after arterial ligationItem Metadata only The enhancing effect of peripheral physical activity on spatial memory by elevating central neurotrophic factor and synaptic plasticity-related proteins in the hippocampus of adolescent rats(2023-12-01) Surakul P.; Ngampramuan S.; Surakul P.; Mahidol Universityby having the rats do voluntary wheel running throughout P25-P40. The Morris water maze task was performed on P40 for 6 days to study spatial memory. The hippocampal protein expression was ascertained by Western blot analysis. We found that physical activityItem Metadata only Cognitive impairment and hippocampal neuronal damage in β-thalassaemia mice(2024-12-01) Pholngam N.; Jamrus P.; Viwatpinyo K.; Kiatpakdee B.; Vadolas J.; Chaichompoo P.; Ngampramuan S.; Svasti S.; Pholngam N.; Mahidol Universitymotor cortex, layer 2/3 area was found. Interestingly, impaired learning and memory function accessed by a Morris water maze test was observed and correlated with a reduced number of living pyramidal neurons in hippocampus at the CA3 region in βItem Metadata only Oral calcium and vitamin D supplements differentially alter exploratory, anxiety-like behaviors and memory in male rats(2023-01-01) Lapmanee S.; Bhubhanil S.; Sriwong S.; Yuajit C.; Wongchitrat P.; Teerapornpuntakit J.; Suntornsaratoon P.; Charoenphandhu J.; Charoenphandhu N.; Mahidol University, whereas certain forms of calcium supplement (e.g., CaCO3) probably interfere with memory function. However, it was unclear whether a long-term use of ionized calcium (calcium chloride in drinking water ad libitum), vitamin D supplement (oral gavage.... After 4 weeks of treatment, anxiety-, exploration- and recognition memory-related behaviors were evaluated by elevated pulse-maze (EPM), open field test (OFT), and novel object recognition (NOR), respectively. The hippocampi were investigatedItem Metadata only Therapeutic potential of Thai herbal formula for cognitive impairment: A metabolomics approach for Comprehensive Insights(2024-04-15) Akarasereenont P.; Pattanapholkornsakul S.; Limsuvan S.; Mamaethong D.; Booranasubkajorn S.; Pakaprot N.; Tripatara P.; Pilakasiri K.; Akarasereenont P.; Mahidol Universityanalysis using LC-MS/QTof and toxicity study. The rats were evaluated for spatial learning and memory using the Morris water maze. The results showed that 78 known metabolites and 10 tentative pathways altered after chronic cerebral hypoperfusion, althoughItem Metadata only Concomitant increased brain-derived neurotrophic factor and interleukin-6 protein expression with postnatal exercise-associated spatial memory preservation in prenatal-stressed rat offspring(2026-02-01) Surakul P.; Vanichviriyakit R.; Sutiwisesak R.; Ngampramuan S.; Surakul P.; Mahidol Universitywas tested with the Morris water maze (MWM) during P36–40. The effect of prenatal stress and the potential effects of the VWR on the levels of hippocampal synaptic proteins, brain-derived neurotrophic factor (BDNF), and interleukin (IL)-6 in the rat offspringItem Metadata only Synergistic Effects of Probiotic Strains and Abelmoschus esculentus (L.) Moench (Okra) on Learning and Memory Impairment in Amnestic Rat Models(2026-04-01) Chaima N.; Photi T.; Klinprathap K.; Choompoo N.; Lekchaoum T.; Tanasawet S.; Suttikul S.; Chonpathompikunlert P.; Khongsombat O.; Chaima N.; Mahidol Universityintracerebroventricularly with Aβ25-35to induce Alzheimer’s disease-like symptoms. Rats in the Aβ-treated group showed significant impairments in both spatial and recognition memory, as evidenced by decreased retention time in the Morris’s water maze and reduced