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Publication Metadata only Effects of social isolation rearing on learning in the Morris water maze(1996-04-09) Noppamars Wongwitdecha; Charles Alexander Marsden; University of Nottingham; Mahidol Universityexperiments investigated the effects of isolation rearing on place navigation in the Morris water maze. Two complementary paradigms were studied: isolation and socially reared rats were exposed to the water maze either without drug pretreatment or following... later place learning and reversal learning were determined using the Morris water maze. The time taken to locate the submerged island (escape latency) was used as the measure of learning ability. The results showed that place learning, and reversalPublication Metadata only Effects of non-spatial pre-training on learning and memory impairment detection in the morris water maze(2018-02-01) Phanit Koomhin; Apsorn Sattayakhom; Sarawoot Palipoch; Chuchard Punsawad; Sompol Tapechum; Walailak University; Faculty of Medicine, Siriraj Hospital, Mahidol University© 2018, Walailak University. All rights reserved. One of the most popular learning and memory tests is the Morris water maze. The Morris water maze is a circular pool filled with water with a hidden platform under the water surface. The test... to leave the water. In the experiment, animals use environmental cues to find the location of the hidden platform in the pool. After consecutive training days, animals can more quickly locate the hidden platform. The last day of the task involves a memoryPublication Open Access Enriched environment attenuates changes in Water-Maze performance and BDNF level caused by prenatal alcohol exposure(2014-05-15) Rungpiyada Tipyasang; Sarun Kunwittaya; Sujira Mukda1; Nittaya J Kotchabhakdi; Naiphinich Kotchabhakdi; Mahidol University. Institute of Molecular Biosciences; Mahidol University. National Institute for Child and Family Development; Mahidol University. Ramathibodi Hospital. Faculty of Medicinecage (CC, CFAS) or enriched living conditions (CE, EFAS) for 8 weeks. Neurobehavioral studies both on hippocampus-dependent spatial learning and place and cue learning strategy, a striatum-dependent test, were measured by the Morris water maze taskPublication Metadata only Enriched environment attenuates changes in water-maze performance and bdnf level caused by prenatal alcohol exposure(2014-05-15) Rungpiyada Tipyasang; Sarun Kunwittaya; Sujira Mukda; Nittaya J. Kotchabhakdi; Naiphinich Kotchabhakdi; Mahidol University, CFAS) or enriched living conditions (CE, EFAS) for 8 weeks. Neurobehavioral studies both on hippocampus-dependent spatial learning and place and cue learning strategy, a striatum-dependent test, were measured by the Morris water maze task. MoreoverItem Metadata only Effects of alcohol and taurine supplementation on body growth, maternal behaviors, and offspring hippocampal dependent water maze learning(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Pilant Ananchaipatana-Auitragoon; Naiphinich Kotchabhakdi; Nuanchan Jutapakdeegul; Ottersen, Ole Pette; Amiry-Moghaddam, Mahmoodand behaviors were monitored. Offspring body weights were recorded. Adult offspring were tested on learning and memory using a water maze during the course of a 6-day task. Percentage of escapes, escape latency and learning curves were analyzed. It was found...ศึกษาโดยทดสอบจาก Water Maze เป็นเวลา 6 วัน ข้อมูลที่ถูกรวบรวมได้แก่ อัตราการการเจอแท่นพักใต้น้ำ ระยะเวลาที่ใช้ในการหาแท่นพัก และกราฟการเรียนรู้ถูกนำมาวิเคราะห์ ผลการทดลองพบว่าการดื่มแอลกอฮอล์ในแม่ขณะตั้งครรภ์ส่งผลกระทบร้ายแรงต่อลูกตั้งแต่การเจริญเติบโตในPublication Open Access Neuroprotection of HydroxynicotinylAmide 18 against Lipid Peroxidationand,Memory Impairment(2002) Opa Vajragupta; Orawan Monthakantirat; Preecha Boonchoong; Hiroshi Watanabe; Penchom Peungvicha; Mahidol Univesity. Faculty of Pharmacy. Department of Pharmaceutical Chemistryby methamphetamine (MAP), but did not reduce locomotor activity in normal condition as 12P did. The suppression demonstrated the enhancement of brain delivery and the antagonism against aberrant dopamine release. In water maze test, 18 (100 mg/kg, i.p.) as well as 12Publication Metadata only Cognitive Improvements in a Mouse Model with Substituted 1,2,3-Triazole Agonists for Nicotinic Acetylcholine Receptors(2015-08-19) Kuntarat Arunrungvichian; Chantana Boonyarat; Valery V. Fokin; Palmer Taylor; Opa Vajragupta; Mahidol University; Khon Kaen University; Scripps Research Institute; University of California, San Diego), and water maze, were performed in scopolamine-induced amnesic mice. Intraperitoneal injection of these two compounds significantly improved the cognitive impairment in a modified Y-maze test (5 μmol/kg for IND8 and 10 μmol/kg for QND8), ORT (10 μmol/kg...), and water maze test (25 μmol/kg). For delay induced memory deficit or natural memory loss in mice, IND8 and QND8 at 10 μmol/kg were able to enhance memory comparable to PNU-282987 when evaluated using ORT time delay model. Cognitive enhancement of IND8Publication Metadata only Effects of Raw Garlic on Physical Performance and Learning Behaviour in Rats(2002-12-01) Nongluck Sookvanichsilp; Chongkol Tiangda; Pirin Yuennan; Mahidol Universityat doses of 1 and 2 g (of raw garlic)/kg/day were given orally to group 1 and group 2, respectively, while pentoxifylline dispersion at a dose of 200 mg/kg/day was given to group 3. Group 4 served as the control group and was given water. AH tests (maze... with antiplatelet activity. The tests were designated as experiment A and experiment B, both conducted in two consecutive 4-week sessions. In experiment A, the rats performed in a learning maze model during the first 4 weeks then followed by moving along the ropePublication Metadata only Reversible short-term and delayed long-term cognitive impairment induced by chronic mild cerebral hypoperfusion in rats(2013-08-01) Khwanjai Thong-Asa; Supin Chompoopong; Mayuree H. Tantisira; Kanokwan Tilokskulchai; Mahidol University; Kasetsart University; Chulalongkorn University; Burapha University) were evaluated repeatedly by the radial arm water maze at 6 days, and 1, 2 and 4 months after surgery. The spatial performance was re-assessed by the Morris water maze when the rats were 18 months old. The present results revealed that the rCCAO ratsPublication Metadata only Neuroprotective effects of quercetin, rutin and okra (Abelmoschus esculentus Linn.) in dexamethasone-treated mice(2011-10-01) Walaiporn Tongjaroenbuangam; Nootchanart Ruksee; Piyanete Chantiratikul; Noppakun Pakdeenarong; Watee Kongbuntad; Piyarat Govitrapong; Mahasarakham University; Mahidol Universityusing the Morris water maze test. The results showed that the mice treated with dexamethasone had prolonged water maze performance latencies and shorter time spent in the target quadrant while mice pretreated with quercetin, rutin or okra extract prior