Browsing by Author "Bartosińska J."
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Item Metadata only Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study(2026-01-01) Kulthanan K.; Bernstein J.A.; Rudenko M.; Salameh P.; Komoltri C.; Hameed Z.A.; Adışen E.; Al Abri S.; Al-Ahmad M.; Al Hinai B.; Allenova A.; Alshareef S.; Angkoolpakdeekul N.; Arnaout R.; Bartosińska J.; Cherrez-Ojeda I.; Chularojanamontri L.; Criado P.R.; Elsaeed H.; Criado R.F.J.; Farahat A.; Calle C.A.G.; Giménez-Arnau A.M.; Godse K.; Gotua M.; Gülengül M.; Hide M.; Inomata N.; Jung C.G.; Kasperska-Zając A.; Khoshkhui M.; Kolkhir P.; Krasowska D.; Laomoleethorn J.; Maiorowa A.; Manuskiatti P.; Meshkova R.; Mijakoski D.; Muñoz M.; Nasr I.; de Aquino Arnoldi D.N.S.; Kara R.Ö.; Paringkarn T.; Pérez-Manich J.; Podder I.; Robles-Velasco K.; Rosmaninho I.; Saengthong-aram P.; Shengelidze G.; Sittiwanaruk S.; Tafrishi R.; Mitrevska N.T.; Trajkova V.; Tuchinda P.; Viriyaskultorn N.; Wannawittayapa T.; Wattanasillawat P.; Wilson A.; Ye Y.M.; Zalewska-Janowska A.; Maurer M.; Zuberbier T.; Kulthanan K.; Mahidol UniversityBackground and Objective: Symptomatic dermographism (SD), the most common chronic inducible urticaria subtype, manifests as strip-shaped, pruritic wheals after skin friction. Conclusive data on its associated factors are limited, and direct comparisons between individuals with and without SD remain scarce. We aimed to identify factors associated with SD internationally. Methods: The PREVALENCE-D (Prevalence Estimation of Dermographism) study was an international cross-sectional survey conducted from 2021 to 2024 across 19 countries. An expert-designed questionnaire diagnosed SD and assessed potential associated factors. SD participants were defined as those who self-reported chronic recurrent urticarial dermographism with itch. Factors associated with SD were identified by comparing participants with and without SD. Results: Of 68,513 participants, 3101 had SD (female 73.3%). Their mean age was 40.2 ± 16.2 years. Key factors associated with SD included atopic dermatitis (adjusted odds ratio [aOR] 4.20, 95% confidence interval [CI] 3.62‒4.88) and allergic rhinitis (aOR 2.11, 95% CI 1.88‒2.37). Participants with at least one atopic condition (allergic rhinitis, atopic dermatitis, or asthma) were significantly more likely to have SD (aOR 2.70, 95% CI 2.47‒2.95). Those with all three atopic conditions had a further increased likelihood of SD (aOR 7.75, 95% CI 5.31‒11.29). Other associations included working and older age groups, female sex, dyslipidemia, and thyroid disease. Conclusions: Atopic dermatitis and allergic rhinitis emerged as the strongest correlates of SD, especially those with all three atopic conditions. Thus, allergic comorbidities should be assessed in SD patients. Further research is needed to clarify the pathophysiological relationship between these conditions and SD. [Item Metadata only The Prevalence of Symptomatic Dermographism: Results of the International UCARE PREVALENCE-D Study(2025-01-01) Kulthanan K.; Bernstein J.A.; Rudenko M.; Salameh P.; Komoltri C.; Adışen E.; Al Abri S.; Al-Ahmad M.; Al-Ahmed N.; Al Hinai B.; Allenova A.; Alshareef S.; Angkoolpakdeekul N.; Arnaout R.; Bartosińska J.; Cherrez-Ojeda I.; Chularojanamontri L.; Criado P.R.; Ensina L.F.; Criado R.F.J.; Calle C.A.G.; Giménez-Arnau A.M.; Godse K.; Gotua M.; Inomata N.; Jantanapornchai N.; Jung C.G.; Kasperska-Zając A.; Khoshkhui M.; Kolkhir P.; Krasowska D.; Laomoleethorn J.; Maiorowa A.; Meshkova R.; Mijakoski D.; Munoz M.; Nanchaipruek Y.; Nasr I.; Kara R.Ö.; Panjapakkul W.; Paringkarn T.; Podder I.; Robles-Velasco K.; Rosmaninho I.; Presa A.R.; Rujitharanawong C.; Saengthong-aram P.; Tafrishi R.; Mitrevska N.T.; Tuchinda P.; Wannawittayapa T.; Wilson A.; Ye Y.M.; Zalewska-Janowska A.; Maurer M.; Zuberbier T.; Kulthanan K.; Mahidol UniversityBackground: The prevalence of symptomatic dermographism (SD) in the general population remains unclear. This study aimed to internationally estimate the prevalence of SD and two other dermographic subtypes—physiological red dermographism and simple urticarial dermographism—among adults worldwide. Methods: The PREVALENCE-D (Prevalence Estimation of Dermographism) study was the largest international, cross-sectional, internet-based investigation conducted by the Urticaria Centers of Reference and Excellence of the Global Allergy and Asthma Excellence Network from 2021 to 2024. A world expert-designed questionnaire was completed by participants from 28 centers across 19 countries to diagnose SD. Participants were recruited into three age groups (18–24, 25–60, and > 60 years), with ≥ 1000 individuals per group per country. We calculated sex- and age-adjusted prevalence estimates internationally and by country, with 95% confidence intervals. Results: Among 59,543 participants worldwide, those with SD had an adjusted point prevalence of 3.20% (95% confidence interval [CI] 2.68%–3.73%) and a lifetime prevalence of 5.94% (95% CI 5.32%–6.56%). The 25–60 years group presented the highest prevalence. Females had higher rates than males, with statistically significant differences across all age groups for both point and lifetime prevalence. Physiological red dermographism had an adjusted point prevalence of 10.02% (95% CI 9.48%–10.55%) and a lifetime prevalence of 33.47% (95% CI 32.01%–34.94%). Simple urticarial dermographism showed an adjusted point prevalence of 1.21% (95% CI 1.08%–1.35%) and a lifetime prevalence of 5.39% (95% CI 4.99%–5.79%). Conclusion: These findings provide comprehensive international estimates of dermographism, particularly SD, and emphasize the need for appropriate healthcare resource allocation and disease recognition.
