Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study
1
Issued Date
2026-01-01
Resource Type
ISSN
11750561
eISSN
11791888
Scopus ID
2-s2.0-105033470834
Journal Title
American Journal of Clinical Dermatology
Rights Holder(s)
SCOPUS
Bibliographic Citation
American Journal of Clinical Dermatology (2026)
Suggested Citation
Kulthanan K., Bernstein J.A., Rudenko M., Salameh P., Komoltri C., Hameed Z.A., Adışen E., Al Abri S., Al-Ahmad M., Al Hinai B., Allenova A., Alshareef S., Angkoolpakdeekul N., Arnaout R., Bartosińska J., Cherrez-Ojeda I., Chularojanamontri L., Criado P.R., Elsaeed H., Criado R.F.J., Farahat A., Calle C.A.G., Giménez-Arnau A.M., Godse K., Gotua M., Gülengül M., Hide M., Inomata N., Jung C.G., Kasperska-Zając A., Khoshkhui M., Kolkhir P., Krasowska D., Laomoleethorn J., Maiorowa A., Manuskiatti P., Meshkova R., Mijakoski D., Muñoz M., Nasr I., de Aquino Arnoldi D.N.S., Kara R.Ö., Paringkarn T., Pérez-Manich J., Podder I., Robles-Velasco K., Rosmaninho I., Saengthong-aram P., Shengelidze G., Sittiwanaruk S., Tafrishi R., Mitrevska N.T., Trajkova V., Tuchinda P., Viriyaskultorn N., Wannawittayapa T., Wattanasillawat P., Wilson A., Ye Y.M., Zalewska-Janowska A., Maurer M., Zuberbier T. Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study. American Journal of Clinical Dermatology (2026). doi:10.1007/s40257-026-01015-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/115875
Title
Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study
Author(s)
Kulthanan K.
Bernstein J.A.
Rudenko M.
Salameh P.
Komoltri C.
Hameed Z.A.
Adışen E.
Al Abri S.
Al-Ahmad M.
Al Hinai B.
Allenova A.
Alshareef S.
Angkoolpakdeekul N.
Arnaout R.
Bartosińska J.
Cherrez-Ojeda I.
Chularojanamontri L.
Criado P.R.
Elsaeed H.
Criado R.F.J.
Farahat A.
Calle C.A.G.
Giménez-Arnau A.M.
Godse K.
Gotua M.
Gülengül M.
Hide M.
Inomata N.
Jung C.G.
Kasperska-Zając A.
Khoshkhui M.
Kolkhir P.
Krasowska D.
Laomoleethorn J.
Maiorowa A.
Manuskiatti P.
Meshkova R.
Mijakoski D.
Muñoz M.
Nasr I.
de Aquino Arnoldi D.N.S.
Kara R.Ö.
Paringkarn T.
Pérez-Manich J.
Podder I.
Robles-Velasco K.
Rosmaninho I.
Saengthong-aram P.
Shengelidze G.
Sittiwanaruk S.
Tafrishi R.
Mitrevska N.T.
Trajkova V.
Tuchinda P.
Viriyaskultorn N.
Wannawittayapa T.
Wattanasillawat P.
Wilson A.
Ye Y.M.
Zalewska-Janowska A.
Maurer M.
Zuberbier T.
Bernstein J.A.
Rudenko M.
Salameh P.
Komoltri C.
Hameed Z.A.
Adışen E.
Al Abri S.
Al-Ahmad M.
Al Hinai B.
Allenova A.
Alshareef S.
Angkoolpakdeekul N.
Arnaout R.
Bartosińska J.
Cherrez-Ojeda I.
Chularojanamontri L.
Criado P.R.
Elsaeed H.
Criado R.F.J.
Farahat A.
Calle C.A.G.
Giménez-Arnau A.M.
Godse K.
Gotua M.
Gülengül M.
Hide M.
Inomata N.
Jung C.G.
Kasperska-Zając A.
Khoshkhui M.
Kolkhir P.
Krasowska D.
Laomoleethorn J.
Maiorowa A.
Manuskiatti P.
Meshkova R.
Mijakoski D.
Muñoz M.
Nasr I.
de Aquino Arnoldi D.N.S.
Kara R.Ö.
Paringkarn T.
Pérez-Manich J.
Podder I.
Robles-Velasco K.
Rosmaninho I.
Saengthong-aram P.
Shengelidze G.
Sittiwanaruk S.
Tafrishi R.
Mitrevska N.T.
Trajkova V.
Tuchinda P.
Viriyaskultorn N.
Wannawittayapa T.
Wattanasillawat P.
Wilson A.
Ye Y.M.
Zalewska-Janowska A.
Maurer M.
Zuberbier T.
Author's Affiliation
Charité – Universitätsmedizin Berlin
Universidade Federal de São Paulo
University of Cincinnati College of Medicine
Sechenov First Moscow State Medical University
Universitat Pompeu Fabra Barcelona
Uniwersytet Medyczny w Lodzi
Mashhad University of Medical Sciences
Slaski Uniwersytet Medyczny w Katowicach
Kuwait University
Medical University of Lublin
Siriraj Hospital
Sakarya Üniversitesi
King Faisal Specialist Hospital & Research Centre
Ajou University School of Medicine
Université Libanaise
Showa University School of Medicine
Gazi University, Faculty of Medicine
Keimyung University (KU), College of Medicine
Universidad Espíritu Santo
SS Cyril and Methodius University Faculty of Medicine
Ministry of Health Kuwait
Royal Hospital
Hiroshima City Hiroshima Citizens Hospital
D Y Patil University, Navi Mumbai
University of Nicosia Medical School
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Gilbert and Rose-Marie Chagoury School of Medicine
Smolensk State Medical Academy
Institut National de Santé Publique, d’Épidémiologie Clinique et de Toxicologie-Liban
Hospital de Viladecans
College of Medicine & Sagore Dutta Hospital
David Tvildiani Medical University
Unidade Local de Saúde Gaia e Espinho
International Balkan University
London Allergy and Immunology Centre
Centro Universitário Faculdade de Medicina do ABC
City General Hospital “8thSeptember”
GA2LEN Collaborating Center
Remedika General Hospital
Emedic Salud
Respiralab Research Group
Universidade Federal de São Paulo
University of Cincinnati College of Medicine
Sechenov First Moscow State Medical University
Universitat Pompeu Fabra Barcelona
Uniwersytet Medyczny w Lodzi
Mashhad University of Medical Sciences
Slaski Uniwersytet Medyczny w Katowicach
Kuwait University
Medical University of Lublin
Siriraj Hospital
Sakarya Üniversitesi
King Faisal Specialist Hospital & Research Centre
Ajou University School of Medicine
Université Libanaise
Showa University School of Medicine
Gazi University, Faculty of Medicine
Keimyung University (KU), College of Medicine
Universidad Espíritu Santo
SS Cyril and Methodius University Faculty of Medicine
Ministry of Health Kuwait
Royal Hospital
Hiroshima City Hiroshima Citizens Hospital
D Y Patil University, Navi Mumbai
University of Nicosia Medical School
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Gilbert and Rose-Marie Chagoury School of Medicine
Smolensk State Medical Academy
Institut National de Santé Publique, d’Épidémiologie Clinique et de Toxicologie-Liban
Hospital de Viladecans
College of Medicine & Sagore Dutta Hospital
David Tvildiani Medical University
Unidade Local de Saúde Gaia e Espinho
International Balkan University
London Allergy and Immunology Centre
Centro Universitário Faculdade de Medicina do ABC
City General Hospital “8thSeptember”
GA2LEN Collaborating Center
Remedika General Hospital
Emedic Salud
Respiralab Research Group
Corresponding Author(s)
Other Contributor(s)
Abstract
Background and Objective: Symptomatic dermographism (SD), the most common chronic inducible urticaria subtype, manifests as strip-shaped, pruritic wheals after skin friction. Conclusive data on its associated factors are limited, and direct comparisons between individuals with and without SD remain scarce. We aimed to identify factors associated with SD internationally. Methods: The PREVALENCE-D (Prevalence Estimation of Dermographism) study was an international cross-sectional survey conducted from 2021 to 2024 across 19 countries. An expert-designed questionnaire diagnosed SD and assessed potential associated factors. SD participants were defined as those who self-reported chronic recurrent urticarial dermographism with itch. Factors associated with SD were identified by comparing participants with and without SD. Results: Of 68,513 participants, 3101 had SD (female 73.3%). Their mean age was 40.2 ± 16.2 years. Key factors associated with SD included atopic dermatitis (adjusted odds ratio [aOR] 4.20, 95% confidence interval [CI] 3.62‒4.88) and allergic rhinitis (aOR 2.11, 95% CI 1.88‒2.37). Participants with at least one atopic condition (allergic rhinitis, atopic dermatitis, or asthma) were significantly more likely to have SD (aOR 2.70, 95% CI 2.47‒2.95). Those with all three atopic conditions had a further increased likelihood of SD (aOR 7.75, 95% CI 5.31‒11.29). Other associations included working and older age groups, female sex, dyslipidemia, and thyroid disease. Conclusions: Atopic dermatitis and allergic rhinitis emerged as the strongest correlates of SD, especially those with all three atopic conditions. Thus, allergic comorbidities should be assessed in SD patients. Further research is needed to clarify the pathophysiological relationship between these conditions and SD. [