Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study

1

Issued Date

2026-01-01

Resource Type

Article

ISSN

11750561

eISSN

11791888

DOI

10.1007/s40257-026-01015-4

Scopus ID

2-s2.0-105033470834

Journal Title

American Journal of Clinical Dermatology

Rights Holder(s)

SCOPUS

Bibliographic Citation

American Journal of Clinical Dermatology (2026)

Suggested Citation

Kulthanan K., Bernstein J.A., Rudenko M., Salameh P., Komoltri C., Hameed Z.A., Adışen E., Al Abri S., Al-Ahmad M., Al Hinai B., Allenova A., Alshareef S., Angkoolpakdeekul N., Arnaout R., Bartosińska J., Cherrez-Ojeda I., Chularojanamontri L., Criado P.R., Elsaeed H., Criado R.F.J., Farahat A., Calle C.A.G., Giménez-Arnau A.M., Godse K., Gotua M., Gülengül M., Hide M., Inomata N., Jung C.G., Kasperska-Zając A., Khoshkhui M., Kolkhir P., Krasowska D., Laomoleethorn J., Maiorowa A., Manuskiatti P., Meshkova R., Mijakoski D., Muñoz M., Nasr I., de Aquino Arnoldi D.N.S., Kara R.Ö., Paringkarn T., Pérez-Manich J., Podder I., Robles-Velasco K., Rosmaninho I., Saengthong-aram P., Shengelidze G., Sittiwanaruk S., Tafrishi R., Mitrevska N.T., Trajkova V., Tuchinda P., Viriyaskultorn N., Wannawittayapa T., Wattanasillawat P., Wilson A., Ye Y.M., Zalewska-Janowska A., Maurer M., Zuberbier T. Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study. American Journal of Clinical Dermatology (2026). doi:10.1007/s40257-026-01015-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/115875

Title

Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study

Author(s)

Kulthanan K.
 Bernstein J.A.
 Rudenko M.
 Salameh P.
 Komoltri C.
 Hameed Z.A.
 Adışen E.
 Al Abri S.
 Al-Ahmad M.
 Al Hinai B.
 Allenova A.
 Alshareef S.
 Angkoolpakdeekul N.
 Arnaout R.
 Bartosińska J.
 Cherrez-Ojeda I.
 Chularojanamontri L.
 Criado P.R.
 Elsaeed H.
 Criado R.F.J.
 Farahat A.
 Calle C.A.G.
 Giménez-Arnau A.M.
 Godse K.
 Gotua M.
 Gülengül M.
 Hide M.
 Inomata N.
 Jung C.G.
 Kasperska-Zając A.
 Khoshkhui M.
 Kolkhir P.
 Krasowska D.
 Laomoleethorn J.
 Maiorowa A.
 Manuskiatti P.
 Meshkova R.
 Mijakoski D.
 Muñoz M.
 Nasr I.
 de Aquino Arnoldi D.N.S.
 Kara R.Ö.
 Paringkarn T.
 Pérez-Manich J.
 Podder I.
 Robles-Velasco K.
 Rosmaninho I.
 Saengthong-aram P.
 Shengelidze G.
 Sittiwanaruk S.
 Tafrishi R.
 Mitrevska N.T.
 Trajkova V.
 Tuchinda P.
 Viriyaskultorn N.
 Wannawittayapa T.
 Wattanasillawat P.
 Wilson A.
 Ye Y.M.
 Zalewska-Janowska A.
 Maurer M.
 Zuberbier T.

Author's Affiliation

Charité – Universitätsmedizin Berlin
 Universidade Federal de São Paulo
 University of Cincinnati College of Medicine
 Sechenov First Moscow State Medical University
 Universitat Pompeu Fabra Barcelona
 Uniwersytet Medyczny w Lodzi
 Mashhad University of Medical Sciences
 Slaski Uniwersytet Medyczny w Katowicach
 Kuwait University
 Medical University of Lublin
 Siriraj Hospital
 Sakarya Üniversitesi
 King Faisal Specialist Hospital & Research Centre
 Ajou University School of Medicine
 Université Libanaise
 Showa University School of Medicine
 Gazi University, Faculty of Medicine
 Keimyung University (KU), College of Medicine
 Universidad Espíritu Santo
 SS Cyril and Methodius University Faculty of Medicine
 Ministry of Health Kuwait
 Royal Hospital
 Hiroshima City Hiroshima Citizens Hospital
 D Y Patil University, Navi Mumbai
 University of Nicosia Medical School
 Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
 Gilbert and Rose-Marie Chagoury School of Medicine
 Smolensk State Medical Academy
 Institut National de Santé Publique, d’Épidémiologie Clinique et de Toxicologie-Liban
 Hospital de Viladecans
 College of Medicine & Sagore Dutta Hospital
 David Tvildiani Medical University
 Unidade Local de Saúde Gaia e Espinho
 International Balkan University
 London Allergy and Immunology Centre
 Centro Universitário Faculdade de Medicina do ABC
 City General Hospital “8thSeptember”
 GA2LEN Collaborating Center
 Remedika General Hospital
 Emedic Salud
 Respiralab Research Group

Corresponding Author(s)

Kulthanan K.

Other Contributor(s)

Mahidol University

Abstract

Background and Objective: Symptomatic dermographism (SD), the most common chronic inducible urticaria subtype, manifests as strip-shaped, pruritic wheals after skin friction. Conclusive data on its associated factors are limited, and direct comparisons between individuals with and without SD remain scarce. We aimed to identify factors associated with SD internationally. Methods: The PREVALENCE-D (Prevalence Estimation of Dermographism) study was an international cross-sectional survey conducted from 2021 to 2024 across 19 countries. An expert-designed questionnaire diagnosed SD and assessed potential associated factors. SD participants were defined as those who self-reported chronic recurrent urticarial dermographism with itch. Factors associated with SD were identified by comparing participants with and without SD. Results: Of 68,513 participants, 3101 had SD (female 73.3%). Their mean age was 40.2 ± 16.2 years. Key factors associated with SD included atopic dermatitis (adjusted odds ratio [aOR] 4.20, 95% confidence interval [CI] 3.62‒4.88) and allergic rhinitis (aOR 2.11, 95% CI 1.88‒2.37). Participants with at least one atopic condition (allergic rhinitis, atopic dermatitis, or asthma) were significantly more likely to have SD (aOR 2.70, 95% CI 2.47‒2.95). Those with all three atopic conditions had a further increased likelihood of SD (aOR 7.75, 95% CI 5.31‒11.29). Other associations included working and older age groups, female sex, dyslipidemia, and thyroid disease. Conclusions: Atopic dermatitis and allergic rhinitis emerged as the strongest correlates of SD, especially those with all three atopic conditions. Thus, allergic comorbidities should be assessed in SD patients. Further research is needed to clarify the pathophysiological relationship between these conditions and SD. [

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/115875

Collections

Scopus 2026