Browsing by Author "Boontiwa Somsri"

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    In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobactenum tuberculosis
    (2007-03-01) Poonpilas Hongmanee; Kamolchanok Rukseree; Benjamas Buabut; Boontiwa Somsri; Prasit Palittapongarnpim; Faculty of Medicine, Ramathibodi Hospital, Mahidol University; Mahidol University; Thailand National Science and Technology Development Agency
    The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of Mycobacterium tuberculosis were studied. The MICs ranged from 0.062 to 0.25 μg/ml. The MIC50 and MIC90 were 0.125 and 0.25 μg/ml, respectively. These indicate that cloxyquin exhibited good antituberculosis activity, even for multidrug-resistant isolates. Copyright © 2007, American Society for Microbiology. All Rights Reserved.