Publication:
In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobactenum tuberculosis

Issued Date

2007-03-01

Resource Type

Article

ISSN

00664804

DOI

10.1128/AAC.01310-06

Other identifier(s)

2-s2.0-33847617445

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Antimicrobial Agents and Chemotherapy. Vol.51, No.3 (2007), 1105-1106

Suggested Citation

Poonpilas Hongmanee, Kamolchanok Rukseree, Benjamas Buabut, Boontiwa Somsri, Prasit Palittapongarnpim In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobactenum tuberculosis. Antimicrobial Agents and Chemotherapy. Vol.51, No.3 (2007), 1105-1106. doi:10.1128/AAC.01310-06 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/24973

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Title

In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobactenum tuberculosis

Author(s)

Poonpilas Hongmanee
 Kamolchanok Rukseree
 Benjamas Buabut
 Boontiwa Somsri
 Prasit Palittapongarnpim

Other Contributor(s)

Faculty of Medicine, Ramathibodi Hospital, Mahidol University
 Mahidol University
 Thailand National Science and Technology Development Agency

Abstract

The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of Mycobacterium tuberculosis were studied. The MICs ranged from 0.062 to 0.25 μg/ml. The MIC50 and MIC90 were 0.125 and 0.25 μg/ml, respectively. These indicate that cloxyquin exhibited good antituberculosis activity, even for multidrug-resistant isolates. Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Keyword(s)

Medicine
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/24973

Collections

Scopus 2006-2010