Browsing by Author "Knokwan Sawang"

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    Anhydrocochlioquinone A, a new antitumor compound from Bipolaris oryzae
    (2007-07-23) Preecha Phuwapraisirisan; Knokwan Sawang; Pongpun Siripong; Santi Tip-pyang; Mahidol University; Chulalongkorn University; National Cancer Institute Thailand
    In the search for antitumor compounds from Bipolaris oryzae, the coexistence of ophiobolins and cochlioquinones is reported for the first time. Of the compounds isolated, anhydrocochlioquinone A (7) was identified as a new antitumor agent. The structure of 7 was fully characterized by spectroscopic data, including COSY, HSQC, HMBC, and NOESY. The cytotoxicity of isolated compounds against HeLa and KB cells is also described. © 2007 Elsevier Ltd. All rights reserved.