Publication: Anhydrocochlioquinone A, a new antitumor compound from Bipolaris oryzae
2
Issued Date
2007-07-23
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ISSN
00404039
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2-s2.0-34250855030
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Mahidol University
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SCOPUS
Bibliographic Citation
Tetrahedron Letters. Vol.48, No.30 (2007), 5193-5195
Suggested Citation
Preecha Phuwapraisirisan, Knokwan Sawang, Pongpun Siripong, Santi Tip-pyang Anhydrocochlioquinone A, a new antitumor compound from Bipolaris oryzae. Tetrahedron Letters. Vol.48, No.30 (2007), 5193-5195. doi:10.1016/j.tetlet.2007.05.151 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/24161
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Title
Anhydrocochlioquinone A, a new antitumor compound from Bipolaris oryzae
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Abstract
In the search for antitumor compounds from Bipolaris oryzae, the coexistence of ophiobolins and cochlioquinones is reported for the first time. Of the compounds isolated, anhydrocochlioquinone A (7) was identified as a new antitumor agent. The structure of 7 was fully characterized by spectroscopic data, including COSY, HSQC, HMBC, and NOESY. The cytotoxicity of isolated compounds against HeLa and KB cells is also described. © 2007 Elsevier Ltd. All rights reserved.