Publication:
Anhydrocochlioquinone A, a new antitumor compound from Bipolaris oryzae

Issued Date

2007-07-23

Resource Type

Article

ISSN

00404039

DOI

10.1016/j.tetlet.2007.05.151

Other identifier(s)

2-s2.0-34250855030

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Tetrahedron Letters. Vol.48, No.30 (2007), 5193-5195

Suggested Citation

Preecha Phuwapraisirisan, Knokwan Sawang, Pongpun Siripong, Santi Tip-pyang Anhydrocochlioquinone A, a new antitumor compound from Bipolaris oryzae. Tetrahedron Letters. Vol.48, No.30 (2007), 5193-5195. doi:10.1016/j.tetlet.2007.05.151 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/24161

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Title

Anhydrocochlioquinone A, a new antitumor compound from Bipolaris oryzae

Author(s)

Preecha Phuwapraisirisan
 Knokwan Sawang
 Pongpun Siripong
 Santi Tip-pyang

Other Contributor(s)

Mahidol University
 Chulalongkorn University
 National Cancer Institute Thailand

Abstract

In the search for antitumor compounds from Bipolaris oryzae, the coexistence of ophiobolins and cochlioquinones is reported for the first time. Of the compounds isolated, anhydrocochlioquinone A (7) was identified as a new antitumor agent. The structure of 7 was fully characterized by spectroscopic data, including COSY, HSQC, HMBC, and NOESY. The cytotoxicity of isolated compounds against HeLa and KB cells is also described. © 2007 Elsevier Ltd. All rights reserved.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/24161

Collections

Scopus 2006-2010