Browsing by Author "Sanha Panichajakul"

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    Azadirachtin derivatives from seed kernels of Azadirachta excelsa
    (2005-07-01) Somdej Kanokmedhakul; Kwanjai Kanokmedhakul; Thirada Prajuabsuk; Sanha Panichajakul; Piyanan Panyamee; Samran Prabpai; Palangpon Kongsaeree; Khon Kaen University; Mahidol University
    Three new azadirachtin derivatives, named azadirachtins O-Q (1-3), along with the known azadirachtin B (4), azadirachtin L (5), azadirachtin M (6) 11α-azadirachtin H (7), 11β-azadirachtin H (8), and azadirachtol (9) were isolated from seed kernels of Azadirachta excelsa. Their structures were established by spectroscopic techniques, and the structure of 3 was confirmed by X-ray analysis. Compounds 1-7 and 9 exhibited toxicity to the diamondback moth (Plutella xylostella) with an LD50 of 0.75-1.92 μg/g body weight, in 92 h. © 2005 American Chemical Society and American Society of Pharmacognosy.