Publication: Azadirachtin derivatives from seed kernels of Azadirachta excelsa
Issued Date
2005-07-01
Resource Type
ISSN
01633864
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2-s2.0-23844514717
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Natural Products. Vol.68, No.7 (2005), 1047-1050
Suggested Citation
Somdej Kanokmedhakul, Kwanjai Kanokmedhakul, Thirada Prajuabsuk, Sanha Panichajakul, Piyanan Panyamee, Samran Prabpai, Palangpon Kongsaeree Azadirachtin derivatives from seed kernels of Azadirachta excelsa. Journal of Natural Products. Vol.68, No.7 (2005), 1047-1050. doi:10.1021/np050064t Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16322
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Title
Azadirachtin derivatives from seed kernels of Azadirachta excelsa
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Abstract
Three new azadirachtin derivatives, named azadirachtins O-Q (1-3), along with the known azadirachtin B (4), azadirachtin L (5), azadirachtin M (6) 11α-azadirachtin H (7), 11β-azadirachtin H (8), and azadirachtol (9) were isolated from seed kernels of Azadirachta excelsa. Their structures were established by spectroscopic techniques, and the structure of 3 was confirmed by X-ray analysis. Compounds 1-7 and 9 exhibited toxicity to the diamondback moth (Plutella xylostella) with an LD50 of 0.75-1.92 μg/g body weight, in 92 h. © 2005 American Chemical Society and American Society of Pharmacognosy.