Browsing by Author "T. C. Saglik Bakanligi, Taksim Egitim ve Arastirma Hastanesi"

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    Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: A prospective multicentre study (WISS Study)
    (2015-12-16) Massimo Sartelli; Fikri M. Abu-Zidan; Fausto Catena; Ewen A. Griffiths; Salomone Di Saverio; Raul Coimbra; Carlos A. Ordoñez; Ari Leppaniemi; Gustavo P. Fraga; Federico Coccolini; Ferdinando Agresta; Asrhaf Abbas; Saleh Abdel Kader; John Agboola; Adamu Amhed; Adesina Ajibade; Seckin Akkucuk; Bandar Alharthi; Dimitrios Anyfantakis; Goran Augustin; Gianluca Baiocchi; Miklosh Bala; Oussama Baraket; Savas Bayrak; Giovanni Bellanova; Marcelo A. Beltràn; Roberto Bini; Matthew Boal; Andrey V. Borodach; Konstantinos Bouliaris; Frederic Branger; Daniele Brunelli; Marco Catani; Asri Che Jusoh; Alain Chichom-Mefire; Gianfranco Cocorullo; Elif Colak; David Costa; Silvia Costa; Yunfeng Cui; Geanina Loredana Curca; Terry Curry; Koray Das; Samir Delibegovic; Zaza Demetrashvili; Isidoro Di Carlo; Nadezda Drozdova; Tamer El Zalabany; Mushira Abdulaziz Enani; Mario Faro; Mahir Gachabayov; Teresa Giménez Maurel; Georgios Gkiokas; Carlos Augusto Gomes; Ricardo Alessandro Teixeira Gonsaga; Gianluca Guercioni; Ali Guner; Sanjay Gupta; Sandra Gutierrez; Martin Hutan; Orestis Ioannidis; Arda Isik; Yoshimitsu Izawa; Sumita A. Jain; Mantas Jokubauskas; Aleksandar Karamarkovic; Saila Kauhanen; Robin Kaushik; Jakub Kenig; Vladimir Khokha; Jae Il Kim; Victor Kong; Renol Koshy; Avidyl Krasniqi; Ashok Kshirsagar; Zygimantas Kuliesius; Konstantinos Lasithiotakis; Pedro Leão; Jae Gil Lee; Miguel Leon; Aintzane Lizarazu Pérez; Varut Lohsiriwat; Eudaldo López-Tomassetti Fernandez; Eftychios Lostoridis; Raghuveer Mn; Piotr Major; Athanasios Marinis; Daniele Marrelli; Aleix Martinez-Perez; Sanjay Marwah; Michael McFarlane; Renato Bessa Melo; Cristian Mesina; Nick Michalopoulos; Radu Moldovanu; Ouadii Mouaqit; Akutu Munyika; Ionut Negoi; Ioannis Nikolopoulos; Gabriela Elisa Nita; Macerata Hospital; College of Medicine and Health Sciences United Arab Emirates University; Maggiore Hospital; Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust; Ospedale Maggiore; University of California, San Diego; Universidad del Valle, Cali; Helsinki University Hospital; Universidade Estadual de Campinas; Papa Giovanni XXIII Hospital; General Surgery; Mansoura University, Faculty of Medicine; Al Ain Hospital; University of Ilorin; Ahmadu Bello University; LAUTECH Teaching Hospital; Mustafa Kemal Universitesi; King Fahad Medical City; Primary Health Care Centre of Kissamos; University of Zagreb School of Medicine; Brescia Civil Hospital; Hadassah University Medical Centre; Regional Hospital of Bizerte; T. C. Saglik Bakanligi, Taksim Egitim ve Arastirma Hastanesi; Ospedale S. Chiara; Hospital de La Serena; SG Bosco Hospital; Novosibirsk State Medical University; University Hospital of Larissa; CHU Angers; Ospedale di Città di Castello; Universita degli Studi di Roma La Sapienza; Kuala Krai Hospital; Regional Hospital; Policlinico Paolo Giaccone; Samsun Education and Research Hospital; Universitat d'Alacant; CHVNG/E; Tianjin Nankai Hospital; Emergency Municipal Hospital Pascani; Adana Numune Training and Research Hospital; University Clinical Center; Kipshidze Central University Hospital; Hamad General Hospital; Pauls Stradins Clinical University Hospital; Bahrain Defence Force Royal Medical Services; Fundacao Universitaria do ABC, Faculdade de Medicina do ABC; Vladimir City Clinical Hospital of Emergency Medicine; Hospital Miguel Servet; Aretaieion Hospital; Hospital Universitário Terezinha de Jesus; Hospital Escola Padre Albino; Ascoli Piceno Hospital; Trabzon Kanuni Training and Research Hospital; Government Medical College & Hospital Chandigarh; University Hospital in Bratislava; General Hospital of Kavala; Mengucek Gazi Training and Research Hospital; Jichi Medical University; S. M. S. Hospital; Lithuanian University of Health Sciences; University of Belgrade; Turun Yliopistollinen Keskussairaala; Uniwersytet Jagiellonski w Krakowie; City Hospital; Inje University, College of Medicine; Edendale Hospital; University Clinical Center of Kosovo; Krishna Hospital; Vilniaus universitetas; NHS Foundation Trust; Universidade do Minho, Escola de Ciencias da Saude; Yonsei University College of Medicine; Hospital Universitario La Paz; Hospital Universitario Donostia; Mahidol University; Hospital Insular, Las Palmas; Kavala General Hospital; Mysore Medical College; Collegium Medicum Uniwersytet Jagiellonskiego; Tzanion General Hospital; Le Scotte Hospital; University Hospital; Pandit Bhagwat Dayal Sharma Postgraduate Institute of Medical Sciences; University Hospital of the West Indies; Sao Joao Hospital; Emergency Hospital of Craiova; Aristotle University of Thessaloniki; CH Armentieres; National Institute of Hygiene; Onandjokwe Hospital; Emergency Hospital of Bucharest; National Health Service
    © 2015 Sartelli et al. Background: To validate a new practical Sepsis Severity Score for patients with complicated intra-abdominal infections (cIAIs) including the clinical conditions at the admission (severe sepsis/septic shock), the origin of the cIAIs, the delay in source control, the setting of acquisition and any risk factors such as age and immunosuppression. Methods: The WISS study (WSES cIAIs Score Study) is a multicenter observational study underwent in 132 medical institutions worldwide during a four-month study period (October 2014-February 2015). Four thousand five hundred thirty-three patients with a mean age of 51.2years (range 18-99) were enrolled in the WISS study. Results: Univariate analysis has shown that all factors that were previously included in the WSES Sepsis Severity Score were highly statistically significant between those who died and those who survived (p < 0.0001). The multivariate logistic regression model was highly significant (p < 0.0001, R2 = 0.54) and showed that all these factors were independent in predicting mortality of sepsis. Receiver Operator Curve has shown that the WSES Severity Sepsis Score had an excellent prediction for mortality. A score above 5.5 was the best predictor of mortality having a sensitivity of 89.2%, a specificity of 83.5% and a positive likelihood ratio of 5.4. Conclusions: WSES Sepsis Severity Score for patients with complicated Intra-abdominal infections can be used on global level. It has shown high sensitivity, specificity, and likelihood ratio that may help us in making clinical decisions.