Browsing by Author "Thailand Institute for Functional Medicine"

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    The microbiota-mediated dietary and nutritional interventions for COVID-19
    (2021-05-01) Amin Gasmi; Torsak Tippairote; Pavan Kumar Mujawdiya; Massimiliano Peana; Alain Menzel; Maryam Dadar; Asma Gasmi Benahmed; Geir Bjørklund; Ramathibodi Hospital; Council for Nutritional and Environmental Medicine; Razi Vaccine & Serum Research Institute, Iran; Laboratoires Reunis Kutter-Lieners-Hastert Centre Langwies; Università degli Studi di Sassari; Birla Institute of Technology and Science, Pilani; Thailand Institute for Functional Medicine; Académie Internationale de Médecine Dentaire Intégrative; Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée
    Worldwide, scientists are looking for specific treatment for COVID-19. Apart from the antiviral approach, the interventions to support healthy immune responses to the virus are feasible through diet, nutrition, and lifestyle approaches. This narrative review explores the recent studies on dietary, nutritional, and lifestyle interventions that influence the microbiota-mediated immunomodulatory effects against viral infections. Cumulative studies reported that the airway microbiota and SARS-CoV-2 leverage each other and determine the pathogen-microbiota-host responses. Cigarette smoking can disrupt microbiota abundance. The composition and diversification of intestinal microbiota influence the airway microbiota and the innate and adaptive immunity, which require supports from the balance of macro- and micronutrients from the diet. Colorful vegetables supplied fermentable prebiotics and anti-inflammatory, antioxidant phytonutrients. Fermented foods and beverages support intestinal microbiota. In sensitive individuals, the avoidance of the high immunoreactive food antigens contributes to antiviral immunity. This review suggests associations between airway and intestinal microbiota, antiviral host immunity, and the influences of dietary, nutritional, and lifestyle interventions to prevent the clinical course toward severe COVID-19.