Publication: The microbiota-mediated dietary and nutritional interventions for COVID-19
Issued Date
2021-05-01
Resource Type
ISSN
15217035
15216616
15216616
Other identifier(s)
2-s2.0-85104157796
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical Immunology. Vol.226, (2021)
Suggested Citation
Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Massimiliano Peana, Alain Menzel, Maryam Dadar, Asma Gasmi Benahmed, Geir Bjørklund The microbiota-mediated dietary and nutritional interventions for COVID-19. Clinical Immunology. Vol.226, (2021). doi:10.1016/j.clim.2021.108725 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/77296
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Title
The microbiota-mediated dietary and nutritional interventions for COVID-19
Other Contributor(s)
Ramathibodi Hospital
Council for Nutritional and Environmental Medicine
Razi Vaccine & Serum Research Institute, Iran
Laboratoires Reunis Kutter-Lieners-Hastert Centre Langwies
Università degli Studi di Sassari
Birla Institute of Technology and Science, Pilani
Thailand Institute for Functional Medicine
Académie Internationale de Médecine Dentaire Intégrative
Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée
Council for Nutritional and Environmental Medicine
Razi Vaccine & Serum Research Institute, Iran
Laboratoires Reunis Kutter-Lieners-Hastert Centre Langwies
Università degli Studi di Sassari
Birla Institute of Technology and Science, Pilani
Thailand Institute for Functional Medicine
Académie Internationale de Médecine Dentaire Intégrative
Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée
Abstract
Worldwide, scientists are looking for specific treatment for COVID-19. Apart from the antiviral approach, the interventions to support healthy immune responses to the virus are feasible through diet, nutrition, and lifestyle approaches. This narrative review explores the recent studies on dietary, nutritional, and lifestyle interventions that influence the microbiota-mediated immunomodulatory effects against viral infections. Cumulative studies reported that the airway microbiota and SARS-CoV-2 leverage each other and determine the pathogen-microbiota-host responses. Cigarette smoking can disrupt microbiota abundance. The composition and diversification of intestinal microbiota influence the airway microbiota and the innate and adaptive immunity, which require supports from the balance of macro- and micronutrients from the diet. Colorful vegetables supplied fermentable prebiotics and anti-inflammatory, antioxidant phytonutrients. Fermented foods and beverages support intestinal microbiota. In sensitive individuals, the avoidance of the high immunoreactive food antigens contributes to antiviral immunity. This review suggests associations between airway and intestinal microbiota, antiviral host immunity, and the influences of dietary, nutritional, and lifestyle interventions to prevent the clinical course toward severe COVID-19.