Browsing by Author "Yuliang Dong"

Filter results by typing the first few letters
Now showing 1 - 2 of 2
  • No Thumbnail Available
    PublicationMetadata only
    Author Correction: Chronic Kidney Disease Impairs Bone Defect Healing in Rats (Scientific Reports, (2016), 6, 1, (23041), 10.1038/srep23041)
    (2020-12-01) Weiqing Liu; Ning Kang; Dutmanee Seriwatanachai; Yuliang Dong; Liyan Zhou; Yunfeng Lin; Ling Ye; Xing Liang; Quan Yuan; West China School/Hospital of Stomatology Sichuan University; Mahidol University
    © 2020, The Author(s). An amendment to this paper has been published and can be accessed via a link at the top of the paper.
  • No Thumbnail Available
    PublicationMetadata only
    Effect of resorbable collagen plug on bone regeneration in rat critical-size defect model
    (2016-04-13) Weiqing Liu; Ning Kang; Yuliang Dong; Yuchen Guo; Dan Zhao; Shiwen Zhang; Liyan Zhou; Dutmanee Seriwatanachai; Xing Liang; Quan Yuan; State Key Laboratory of Oral Disease; West China Hospital of Sichuan University; Mahidol University
    © 2016 Wolters Kluwer Health, Inc. All rights reserved. Objective: The purpose of this investigation was to examine the effect of resorbable collagen plug (RCP) on bone regeneration in rat calvarial critical-size defects. Methods: About 5-mm-diameter calvarial defects were created in forty 12-week-old male Sprague-Dawley rats and implanted with or without RCP. Animals were killed at 1, 2, 4, and 8 weeks postoperatively. After being killed, specimens were collected and subjected to microcomputed tomography (mCT) and histological analysis. Results: The mCT showed a significant increase of newly formed bone volume/tissue volume in RCPimplanted defect compared with controls at all designated time points. After 8 weeks, the defects implanted with RCP displayed almost complete closure. Hematoxylin and eosin staining of the decalcified sections confirmed these observations and evidenced active bone regeneration in the RCP group. In addition, Masson's trichrome staining demonstrated that RCP implantation accelerated the process of collagen maturation. Conclusions: The RCP enhances bone regeneration in rat criticalsize cranial defects, which suggest it might be a desired material for bone defect repair.