Journal Issue: JAAS Vol. 8 No. 1
Issued Date
2558
Resource Type
Language
tha
eng
eng
File Type
application/pdf
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
คณะสัตวแพทยศาสตร์ มหาวิทยาลัยมหิดล
Journal Volume
JAAS Volume 8
(2558)
Articles
Nuclear scintigraphic examination in veterinary medicine
(2015) Somkiat Huaijantug; Mahidol University. Faculty of Veterinary Science. Department of Clinical Science and Public Health
The present review will discuss the information of nuclear scintigraphic examination in veterinary
medicine. The main focus is on the introduction of nuclear medicine procedures in animal patients and describes
conventional nuclear medicine (brain scintigraphy, bone scintigraphy, thyroid scintigraphy, inflammation and
oncological scintigraphy). Single photon emission scintigraphy (SPECT) and positron emission tomography
(PET) have recently been developed using for nuclear scintigraphic examination to provide functional and
physiological imaging, the quantification of biochemical processes, molecular interactions, and neoplasias.
Radiopharmaceuticals or radionuclides have a longer physical half-life allowing that need longer acquisition
times used for specific investigation purposes. In veterinary medicine, scintigraphy can be the basis of a sensitive,
specific and non-invasive diagnostic method, which information has been applied to support the diagnostic
process and treatment planning for animal patients.
Possible involvement of glucocorticoids in mycotoxin-induced neuroinflammation
(2015) Boonrat Chantong; Punnee Nusuetrong; Mahidol University. Faculty of Veterinary Science. Department of Pre-clinic and Applied Animal Science
The mycotoxins are commonly encountered in human cereal foods and animal feed throughout the
world as a result of infestation of grains in the field and in storage by the fungi including genus Aspergillus,
Penicillum and Fusarium. Modulation of the inflammatory responses in the central nervous system (CNS)
appears particularly critical role of some relevance mycotoxins such as T-2 toxin, fumonisin B1 and ochratoxin A.
Specifically, mentioned mycotoxins disturbed mitogen-activated protein kinases (MAPKs) as well as nuclear
factor kappa-light-chain-enhancer of activated B cells (NF-κB) which mediate robust induction of proinflammatory
gene expression in both in vitro and in vivo. In CNS, glucocorticoids are powerful endogenous
and therapeutic modulators of inflammation though both MAPKs and NF-κB signaling. In addition, toxicity of
mycotoxins also was altered with glucocorticoid. Taken together, glucocorticoids may possibly involve in the
action of mycotoxins on neuroinflammatory responses. Therefore, factors disturbing glucocorticoid regulation
in CNS such as stress, infection, and xenobiotics may enhance response to mycotoxin toxicity. It is anticipated
that these investigations will be applicable to identify the therapeutic intervention or prevention.
Retinal lesion in a Toxoplasma gondii seropositive Bengal tiger (Panthera tigris) in a private zoo, Kanchanaburi Province
(2015) Areerat Kongcharoen; Ruangrat Buddhirongawatr; Siriporn Tungsudjai; Nareerat Sangkhachai; Poonyapat Sedwisai; Thekhawet Weluwanarak; Tatiyanuch Chamsai; Mahidol University. Faculty of Veterinary Science
One of 25 Bengal tigers (Panthera tigris) at a private zoo in Kanchanaburi Province had seropositive
against Toxoplasma gondii infection. The animals were physical and ophthalmic examined during routine
annual health check in February, 2013. All of them appeared in normal condition and had no signs of illness.
Their blood was tested negative for feline leukemia virus, feline immunodeficiency virus, feline infectious
peritonitis virus and Toxoplasma gondii using molecular detection of viral antigen. The serological test for
T. gondii infection was performed by latex agglutination test. The seropositive tiger was a 9 years old female
tiger which ophthalmic examination also shown a retinal lesion, a spot of hyperreflective area in right fundus of
the right eye. T. gondii had been shown to implicate as a major contributor to retinal lesions in felids.
Serological evidence and lesion found in the Bengal tiger in this study consistent with T. gondii infection. Hence,
it was considered as a potential cause. Further study should be performed to confirm the infection and to
identify risk factors for prevention.
Case report: Bronchoesophageal fistula in mixed breed dog
(2015) Phingphol Charoonrut; Nattapon Riengvirodkij; Chanon Kamta; Mahidol University. Faculty of Veterinary Science
A 10-year-old, male neutered, 10 kg, mixed poodle was presented with a 4-month history of non-productive
cough. The dog was firstly diagnosed pneumonia at the left caudal lung lobe. However, the treatment with
systemic antibiotics, mucolytics and bronchodilators did not improve his clinical signs. Moreover, the regurgitation
with foamy content was developed. The esophagoscopy and contrast radiography with barium sulfate solution
were performed for the definite diagnosis. The bronchoesophageal fistula with secondary pneumonia at the left
caudal lung lobe was diagnosed. The specific treatment for the bronchoesophageal fistula was performed by
the surgical correction via thoracotomy.
Title
JAAS Vol. 8 No. 1
Author's Affiliation
มหาวิทยาลัยมหิดล. คณะสัตวแพทยศาสตร์