Journal Issue: JAAS Vol. 8 No. 2
2
Issued Date
2558
Resource Type
Language
tha
eng
eng
File Type
application/pdf
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
คณะสัตวแพทยศาสตร์ มหาวิทยาลัยมหิดล
Journal Volume
JAAS Volume 8
(2558)
Articles
ความรู้พื้นฐานเกี่ยวกับเซลล์ต้นกำเนิดมีเซนไคม์เพื่อใช้ทางสัตวแพทย์
(2558) ปริญญา สามารถ; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์ศิริราชพยาบาล. ภาควิชาวิทยาภูมิคุ้มกัน
A stem cell is an undifferentiated cell that has special properties for two reasons (1) the ability to increase
the number self-renewal and (2) the ability to be differentiated into many cell types, and can be classified into
two types (1) embryonic stem cells and (2) adult stem cells. Recent reports found that the differentiated cells
can be reprogrammed to embryonic stem-like cells known as induced pluripotent stem cells. In the field of
veterinary medicine, much attention has been paid to mesenchymal stem cells (MSCs), one type of adult stem
cells. Many reports reveal the success for treating animals; however, there are small number of research have
been performed in Thailand. The advantages of using MSCs are it can be easily isolated and cultured, avoiding
ethical problems, having little effect on host immune defense, low costs and can be further applied clinically.
The limitations of using MSCs are purification, proliferation and differentiation capability. Therefore, a basic
science of mesenchymal stem cells is very important for the research question and developments. Thailand
should focus on clinical application for build the confidence and enhance the standard of veterinary medicine
in Thailand in order to compare with veterinary profession from developed countries, especially innovative
new treatment by using mesenchymal stem cells.
Three phase bone scintigraphy in evaluating revascularization and bone formation of natural biomaterial bone graft by using Tc99m MDP in rabbits
(2015) Somkiat Huaijantug; Paranee Yatmark; Somsak Wattananit; Phingphol Charoonrut; Thonnapong Thongpraparn; Rujaporn Chanachai; Mahidol University. Faculty of Veterinary Science; Mahidol University. Faculty of Medicine Siriraj Hospital
Three phase bone scintigraphy (TPBS) examined the viability of bone graft, revascularization, and
bone formation using single photon emission computed tomography (SPECT) and the intravenous injection
of 99M Technetium methylenediphosphonate (99MTc-MDP). Seven New Zealand White rabbits, aged 8 months
had osteotomy of ulna performed, the left ulna substituted for natural biomaterial bone graft, containing
gelatin sponge and hyaluronic acid, and the right ulna was replaced by vascularized autogenous bone graft. A
post-operative scanning of bone using TPBS was done at 7 days and weekly, at week 1, 2, 4, 6, 8, 12 to evaluate
revascularization and bone formation of natural biomaterial bone graft comparing with autogenous bone
graft. The results demonstrated that the perfusion index and RCP of natural biomaterial bone graft and the
autogenous bone graft in phases 1, 2, and 3 had no statistically significant difference when compared in between
each week. The study also showed that, the ratio of the mean counts/pixel of the natural biomaterial bone graft
in phase 3 had slightly lower than autogenous bone graft. This study provided model through which TPBS
could evaluate revascularization and bone formation in this model. Natural biomaterial bone graft may be the
same and as good a revascularization as autogenous bone graft although the bone formation of autogenous
bone graft still has more efficiency than natural biomaterial bone.
ความหลากหลายทางชีวภาพของสัตว์ไม่มีกระดูกสันหลังหน้าดินและคุณภาพน้ำผิวดิน ภายในมหาวิทยาลัยมหิดล จังหวัดนครปฐม
(2558) กัณธิตา ปวีณสกล; พีรวัส ชินตระกูลชัย; ธนศักดิ์ ช่างบรรจง; มหาวิทยาลัยมหิดล. คณะสัตวแพทยศาสตร์. ศูนย์เฝ้าระวังและติดตามโรคจากสัตว์ป่า สัตว์ต่างถิ่นและสัตว์อพยพ
A study on the biodiversity of benthic macroinvertebrates and surface water quality was carried out
from February to April 2015 in five sampling sites located within Mahidol University, Nakhon Pathom Province.
Water quality was assessed using physiochemical parameters in combination with macroinvertebrate
composition and biodiversity indices. Correlations of biodiversity indices and physiochemical parameters were
also determined. A total of 2,641 benthic macroinvertebrates from 16 families in 10 orders were collected
and identified. The most abundant family was Corixidae in the order Hemiptera. Most of physiochemical
parameters indicated that surface water in all study sites were still suitable for aquatic animals. The correlation
analysis showed that temperature, dissolved oxygen (DO) and pH correlated with diversity index (P<0.01).
Thus, benthic macroinvertebrates can be used as a biological indicator for the assessment of water quality.
Title
JAAS Vol. 8 No. 2
Author's Affiliation
มหาวิทยาลัยมหิดล. คณะสัตวแพทยศาสตร์