Publication: Population structure of Angiostrongylus cantonensis (nematoda: Metastrongylidae)in Thailand based on PCR-RAPD markers
Issued Date
2012-11-05
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ISSN
01251562
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2-s2.0-84868151597
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.43, No.3 (2012), 567-573
Suggested Citation
Urusa Thaenkham, Wallop Pakdee, Supaporn Nuamtanong, Wanna Maipanich, Somchit Pubampen, Surapol Sa-nguankiat, Chalit Komalamisra Population structure of Angiostrongylus cantonensis (nematoda: Metastrongylidae)in Thailand based on PCR-RAPD markers. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.43, No.3 (2012), 567-573. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/14524
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Title
Population structure of Angiostrongylus cantonensis (nematoda: Metastrongylidae)in Thailand based on PCR-RAPD markers
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Abstract
Angiostrongylus cantonensis is the causative agent of angiostrongyliasis, which is widely distributed throughout the world. It can specifically infect many species of intermediate and definitive hosts. This study examined the genetic differentiation and population structure using the RAPD-PCR method of parasites obtained from 8 different geographical areas of Thailand. Based on 8 primers, high levels of genetic diversity and low levels of gene flow among populations were found. Using genetic distance and neighbor-joining dendrogram methods, A. cantonensis in Thailand could be divided into two groups with statistically significant genetic differentiation of the two populations. However, genotypic variations and haplotype relationships need to be further elucidated using other markers.