Publication: In vitro phytotherapeutic properties of aqueous extracted adenia viridiflora craib towards civilization diseases
Issued Date
2021-02-02
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14203049
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2-s2.0-85102705785
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Mahidol University
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SCOPUS
Bibliographic Citation
Molecules. Vol.26, No.4 (2021)
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Werawat Wannasaksri, Nattira On-Nom, Chaowanee Chupeerach, Piya Temviriyanukul, Somsri Charoenkiatkul, Uthaiwan Suttisansanee In vitro phytotherapeutic properties of aqueous extracted adenia viridiflora craib towards civilization diseases. Molecules. Vol.26, No.4 (2021). doi:10.3390/molecules26041082 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/76282
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Title
In vitro phytotherapeutic properties of aqueous extracted adenia viridiflora craib towards civilization diseases
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Abstract
Adenia viridiflora Craib. is an indigenous edible plant that became an endangered species due to limited consumption of the local population with unknown reproduction and growth conditions. The plant is used as a traditional herb; however, its health applications lack scientific-based evidence. A. viridiflora Craib. plant parts (old leaves and young shoots) from four areas as Kamphaeng Phet (KP), Muang Nakhon Ratchasima (MN), Pakchong Nakhon Ratchasima (PN), and Uthai Thani (UT) origins were investigated for phenolic compositions and in vitro health properties through the inhibition of key enzymes relevant to obesity (lipase), diabetes (α-glucosidase and dipeptidyl peptidase-IV), Alzheimer’s disease (cholinesterases and α-secretase), and hypertension (angiotensinconverting enzyme). Phenolics including p-coumaric acid, sinapic acid, naringenin, and apigenin were detected in old leaves and young shoots in all plant origins. Old leaves exhibited higher total phenolic contents (TPCs) and total flavonoid contents (TFCs), leading to higher enzyme inhibitory activities than young shoots. Besides, PN and MN with higher TPCs and TFCs tended to exhibit greater enzyme inhibitory activities than others. These results will be useful to promote this plant as a healthy food with valuable medicinal capacities to support its consumption and agricultural stimulation, leading to sustainable conservation of this endangered species.