Publication: Second-line drug susceptibilities of multidrug-resistant tuberculosis strains isolated in Thailand: An update
Issued Date
2014-08-01
Resource Type
ISSN
10273719
Other identifier(s)
2-s2.0-84904563231
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Tuberculosis and Lung Disease. Vol.18, No.8 (2014), 961-963
Suggested Citation
A. Chaiprasert, S. Srimuang, N. Tingtoy, N. Makhao, P. Sirirudeeporn, N. Tomnongdee, O. Theankeaw, S. Charoensook, M. Leechawengwongs, T. Prammananan Second-line drug susceptibilities of multidrug-resistant tuberculosis strains isolated in Thailand: An update. International Journal of Tuberculosis and Lung Disease. Vol.18, No.8 (2014), 961-963. doi:10.5588/ijtld.13.0197 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34221
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Title
Second-line drug susceptibilities of multidrug-resistant tuberculosis strains isolated in Thailand: An update
Abstract
The increasing incidence of multidrug-resistant tuberculosis (MDR-TB) and the emergence of extensively drug-resistant tuberculosis (XDR-TB) globally hamper the successful treatment and effective control of TB. Information on second-line drug susceptibility, which is of utmost importance for patient care, is still limited. This study demonstrates the susceptibilities of 1447 strains of MDR-TB, including 58 XDR-TB strains, isolated from Siriraj Hospital, Bangkok, Thailand, to aminoglycosides, fluoroquinolones, ethionamide (ETH), para-aminosalicylic acid (PAS) and linezolid. Results revealed that 93-94% of the MDR-TB strains were susceptible to aminoglycosides, 85-98% to fluoroquinolones, 78% to ETH, 85% to PAS and 99% to linezolid. © 2014 The Union.