Publication: Prevalence and associating factors of atrial fibrillation in patients with hypertension: a nation-wide study
Issued Date
2016
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eng
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Mahidol University
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BioMed Central
Bibliographic Citation
BMC Cardiovascular Disorders. Vol. 16, (2016), 57
Suggested Citation
Rungroj Krittayaphong, Ram Rangsin, Bandit Thinkhamrop, Hurst, Cameron, Suthee Rattanamongkolgul, Nintita Sripaiboonkij, Ahthit Yindeengam Prevalence and associating factors of atrial fibrillation in patients with hypertension: a nation-wide study. BMC Cardiovascular Disorders. Vol. 16, (2016), 57. doi:10.1186/s12872-016-0232-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/2676
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Title
Prevalence and associating factors of atrial fibrillation in patients with hypertension: a nation-wide study
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Abstract
Background: Atrial fibrillation (AF) is a common cardiac arrhythmia and increases risk of ischemic stroke. Data on
the prevalence of AF in Thailand is lacking especially in patients with hypertension. The objectives of this study
were to determine prevalence of AF in patients with hypertension and to determine factors that are associated
with increased prevalence of AF in a multicenter nationwide study.
Methods: A cross-sectional survey for the national outcome evaluation among hypertensive patients visiting 831
public hospitals in Thailand was conducted between 2011 and 2012 to evaluate status of standard care in
hypertensive patients visiting public Thailand Ministry of Public Health (MoPH) hospitals. Inclusion criteria were
hypertensive patients aged at least 20 years who had received medical care in the targeted hospital for at
least 12 months. The main outcome measurement was AF rhythm, and was measured along with potential
risk factors age, gender and cardiovascular risk factors.
Results: There were 13207 hypertensive patients who had ECG data recorded during the survey. AF was
detected in 457 patients (3.46 %). Prevalence of AF increased with increasing age, was more common in
males and in patients with chronic kidney disease (CKD). Multivariable modelling was conducted to assess
which factors were most associated with increased prevalence of AF, and the results showed older age
followed by male gender, low LDL-cholesterol and increased uric acid levels were the most important risk
factors for AF in this population.
Conclusions: Prevalence of AF in hypertensive patients was 3.46 %. Factors associated with increased risk of
AF are old age, male gender, low LDL-cholesterol and elevated uric acid level.