Publication: Risk of venous thromboembolism in patients with idiopathic pulmonary fibrosis: A systematic review and meta-analysis
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Issued Date
2018-08-09
Resource Type
ISSN
2532179X
11240490
11240490
Other identifier(s)
2-s2.0-85052383190
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Mahidol University
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SCOPUS
Bibliographic Citation
Sarcoidosis Vasculitis and Diffuse Lung Diseases. Vol.35, No.2 (2018), 109-114
Suggested Citation
Boonphiphop Boonpheng, Patompong Ungprasert Risk of venous thromboembolism in patients with idiopathic pulmonary fibrosis: A systematic review and meta-analysis. Sarcoidosis Vasculitis and Diffuse Lung Diseases. Vol.35, No.2 (2018), 109-114. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/46435
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Title
Risk of venous thromboembolism in patients with idiopathic pulmonary fibrosis: A systematic review and meta-analysis
Author(s)
Abstract
© Mattioli 1885. Background: Recent studies have suggested that patients with idiopathic pulmonary fibrosis (IPF) may have a higher risk of venous thromboembolism (VTE) compared to general population even though the results were inconsistent. Objective: To investigate the risk of VTE among patients with IPF. Methods: Comprehensive literature review using MEDLINE and EMBASE database were performed to identify studies that compared the risk of VTE among patients with IPF to general population. Effect estimates from each study were combined together using random effect model, generic inverse variance method of DerSimonian and Laird. Results: Out of 510 retrieved articles, 5 studies met the inclusion criteria and were included in the meta-analysis. A significant risk of VTE in patients with IPF was observed with the pooled risk ratio of 2.11 (95% confidence interval, 1.28-3.48). The heterogeneity was moderate with I 2 of 64%. Conclusion: An approximately 2-fold increased risk of VTE among patients with IPF was observed in this meta-analysis.