Publication: Acute Gastroenteritis in Children of the World: What Needs to Be Done?
Issued Date
2020-05-01
Resource Type
ISSN
15364801
Other identifier(s)
2-s2.0-85084104255
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of pediatric gastroenterology and nutrition. Vol.70, No.5 (2020), 694-701
Suggested Citation
Alfredo Guarino, Juliet Aguilar, James Berkley, Ilse Broekaert, Rodrigo Vazquez-Frias, Lori Holtz, Andrea Lo Vecchio, Toufik Meskini, Sean Moore, Juan F. Rivera Medina, Bhupinder Sandhu, Andrea Smarrazzo, Hania Szajewska, Suporn Treepongkaruna Acute Gastroenteritis in Children of the World: What Needs to Be Done?. Journal of pediatric gastroenterology and nutrition. Vol.70, No.5 (2020), 694-701. doi:10.1097/MPG.0000000000002669 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/56248
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Title
Acute Gastroenteritis in Children of the World: What Needs to Be Done?
Other Contributor(s)
University of the Philippines Manila
Universidad Nacional Mayor de San Marcos
Medical University of Warsaw
Wellcome Trust Research Laboratories Nairobi
University of Oxford
Washington University School of Medicine in St. Louis
University of Virginia
Mohammed V University in Rabat
Università degli Studi di Napoli Federico II
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Bristol Royal Hospital for Children
Uniklinik Köln
Hospital Infantil de Mexico Federico Gomez
Universidad Nacional Mayor de San Marcos
Medical University of Warsaw
Wellcome Trust Research Laboratories Nairobi
University of Oxford
Washington University School of Medicine in St. Louis
University of Virginia
Mohammed V University in Rabat
Università degli Studi di Napoli Federico II
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Bristol Royal Hospital for Children
Uniklinik Köln
Hospital Infantil de Mexico Federico Gomez
Abstract
The incidence of gastroenteritis has greatly reduced due to improved hygiene conditions in developing countries and the use of rotavirus vaccine. Still thousands of children, however, die from gastroenteritis, most of them in poor countries. Yet gastroenteritis management is simple, inexpensive, and effective and is largely the same all over the world. Universal guidelines for gastroenteritis guide the management and include simple interventions put forward early in the course of the disease. Treatment includes rehydration, continuing oral feeding, and anti-infective drugs in selected clinical conditions related to the symptoms or to host-related risk, and possible additional drug treatment to reduce the duration and severity of symptoms. There may be minor geographical differences in the treatment applied due to health care organizations that do not substantially change the standard universal recommendations. Prevention is recommended with sanitation interventions and rotavirus universal immunization. Implementation of those interventions through educational initiatives and local programs in target areas are needed. A series of recommendations for interventions, education, and research priorities are included here with the aim of reducing the burden of gastroenteritis, to be pursued by scientists, physicians, policy makers, and stakeholders involved. They include the need of recommendations for the management of gastroenteritis in malnourished children, in those with chronic conditions, in neonates, and in emergency settings. A reference system to score dehydration, the definition of optimal composition of rehydration solution and the indications for anti-infective therapy are also included. Rotavirus immunization should be actively promoted, and evidence-based guidelines should be universally implemented. Research priorities are also indicated.